Hematopoietic stem cells (HSC) reside in perivascular regions of the bone marrow (BM)
embedded within a complex regulatory unit called the niche. Cellular components of HSC …

The use of mobilized peripheral blood stem cells (PBSCs) has largely replaced the use of
bone marrow as a source of stem cells for both allogeneic and autologous stem cell …

The vast majority of hematopoietic stem cells (HSCs) reside in specialized niches within the
bone marrow during steady state, maintaining lifelong blood cell production. A small number …

The clinical application of hematopoietic stem and progenitor cells (HSPCs) has evolved
from a highly experimental stage in the 1980s to a currently clinically established treatment …

Peripheral blood hematopoietic stem and progenitor cells (HSPCs), mobilized by
granulocyte colony‐stimulating factor, are widely used as a source for both autologous and …

Hematopoietic stem cells (HSC) are a population of precursor cells that posses the capacity
for self-renewal and multilineage differentiation. In the bone marrow (BM), HSCs warrant …

Hematopoietic mobilization by G-CSF is primarily mediated by alterations to the bone
marrow niche by both direct and indirect mechanisms, rather than directly altering HSC …

Recruitment of hematopoietic stem/progenitor cells (HSC) from the bone marrow into
peripheral blood following treatment with chemotherapy and/or cytokines is termed …

The concept of the haematopoietic stem cell (HSC) niche was formulated by Schofield in the
1970s, as a region within the bone marrow containing functional cell types that can maintain …

Steady-state hematopoietic stem cells'(HSCs) self-renewal and differentiation toward their
mature progeny in the adult bone marrow is tightly regulated by cues from the …