Vasodilatory mechanisms in contracting skeletal muscle

PS Clifford, Y Hellsten - Journal of applied physiology, 2004 - journals.physiology.org
Skeletal muscle blood flow is closely coupled to metabolic demand, and its regulation is
believed to be mainly the result of the interplay of neural vasoconstrictor activity and locally …

Vasodilator interactions in skeletal muscle blood flow regulation

Y Hellsten, M Nyberg, LG Jensen… - The Journal of …, 2012 - Wiley Online Library
During exercise, oxygen delivery to skeletal muscle is elevated to meet the increased
oxygen demand. The increase in blood flow to skeletal muscle is achieved by vasodilators …

Mechanical influences on skeletal muscle vascular tone in humans: insight into contraction‐induced rapid vasodilatation

BS Kirby, RE Carlson, RR Markwald… - The Journal of …, 2007 - Wiley Online Library
We tested the hypothesis that mechanical deformation of forearm blood vessels via acute
increases in extravascular pressure elicits rapid vasodilatation in humans. In healthy adults …

Immediate exercise hyperemia: contributions of the muscle pump vs. rapid vasodilation

ME Tschakovsky, DD Sheriff - Journal of Applied …, 2004 - journals.physiology.org
A striking characteristic of the blood flow adaptation at exercise onset is the immediate and
substantial increase in the first few (0–5 s) seconds of exercise. The purpose of this mini …

Regulation of skeletal muscle perfusion during exercise

MD Delp, MH Laughlin - Acta Physiologica Scandinavica, 1998 - Wiley Online Library
For exercise to be sustained, it is essential that adequate blood flow be provided to skeletal
muscle. The local vascular control mechanisms involved in regulating muscle perfusion …

Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs

MJ Joyner, DP Casey - Physiological reviews, 2015 - journals.physiology.org
This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Skeletal muscle vasodilatation at the onset of exercise

PS Clifford - The Journal of physiology, 2007 - Wiley Online Library
The mechanism for exercise hyperaemia is a century old enigma. Much of the research on
the topic has focused on the factors controlling skeletal muscle blood flow during steady …

Exercise hyperaemia: is anything obligatory but the hyperaemia?

MJ Joyner, BW Wilkins - The Journal of physiology, 2007 - Wiley Online Library
Exercise can increase skeletal muscle blood flow by 100‐fold over values observed at rest.
As this value was 3 to 4 times higher than so‐called 'textbook'values at the time it raised a …

Vasodilatation is obligatory for contraction‐induced hyperaemia in canine skeletal muscle

JJ Hamann, JB Buckwalter… - The Journal of …, 2004 - Wiley Online Library
There is a rapid increase in blood flow to active skeletal muscle with the onset of exercise,
but the mechanism (s) eliciting this increase remains elusive. We hypothesized that the rapid …

Control of skeletal muscle perfusion at the onset of dynamic exercise.

MD Delp - Medicine and science in sports and exercise, 1999 - europepmc.org
At the onset of exercise there is a rapid increase in skeletal muscle vascular conductance
and blood flow. Several mechanisms involved in the regulation of muscle perfusion have …