Heparin-based and heparin-inspired hydrogels: size-effect, gelation and biomedical applications

C He, H Ji, Y Qian, Q Wang, X Liu, W Zhao… - Journal of Materials …, 2019 - pubs.rsc.org
Heparin is the highest negatively charged biomolecule, which is a polysaccharide belonging
to the glycosaminoglycan family, and its role as a regulator of various proteins, cells and …

Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications

Y Liang, KL Kiick - Acta biomaterialia, 2014 - Elsevier
Heparin plays an important role in many biological processes via its interaction with various
proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties …

[HTML][HTML] Biomedical applications of engineered heparin-based materials

EN Zare, D Khorsandi, A Zarepour, H Yilmaz… - Bioactive Materials, 2024 - Elsevier
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic
backbone. Due to its fascinating chemical and physical properties, nontoxicity …

Hyaluronic acid-based supramolecular hydrogels for biomedical applications

M Mihajlovic, L Fermin, K Ito… - Multifunctional …, 2021 - iopscience.iop.org
Soft materials, such as hydrogels, are used as scaffolds in tissue engineering and
regenerative medicine to help tissues regenerate and heal. Recently, supramolecular …

Modification and crosslinking strategies for hyaluronic acid‐based hydrogel biomaterials

Z Luo, Y Wang, Y Xu, J Wang, Y Yu - Smart Medicine, 2023 - Wiley Online Library
Hyaluronic acid (HA) is an attractive extracellular matrix‐derived polymer. The related HA‐
based hydrogels are emerging to be the hotspots in the cutting edge of biomaterials. The …

The potential applications of hyaluronic acid hydrogels in biomedicine

E Ahmadian, SM Dizaj, A Eftekhari, E Dalir… - Drug …, 2020 - thieme-connect.com
Hyaluronic acid (HA) is widely used in the biomedicine due to its biocompatibility,
biodegradability, and nontoxic properties. It is crucial for cell signaling role during …

Supramolecular hydrogels: Design strategies and contemporary biomedical applications

J Omar, D Ponsford, CA Dreiss… - Chemistry–An Asian …, 2022 - Wiley Online Library
Self‐assembly of supramolecular hydrogels is driven by dynamic, non‐covalent interactions
between molecules. Considerable research effort has been exerted to fabricate and …

From crosslinking strategies to biomedical applications of hyaluronic acid-based hydrogels: A review

Y Luo, J Tan, Y Zhou, Y Guo, X Liao, L He, D Li… - International journal of …, 2023 - Elsevier
Hyaluronic acid (HA) is not only a natural anionic polysaccharide with excellent
biocompatibility, biodegradability, and moisturizing effect, but also an essential factor that …

Heparin-mimicking polymers: synthesis and biological applications

SJ Paluck, TH Nguyen, HD Maynard - Biomacromolecules, 2016 - ACS Publications
Heparin is a naturally occurring, highly sulfated polysaccharide that plays a critical role in a
range of different biological processes. Therapeutically, it is mostly commonly used as an …

Strategies for hyaluronic acid-based hydrogel design in drug delivery

S Trombino, C Servidio, F Curcio, R Cassano - Pharmaceutics, 2019 - mdpi.com
Hyaluronic acid (HA) is a natural, linear, endogenous polysaccharide that plays important
physiological and biological roles in the human body. Nowadays, among biopolymers, HA is …