Orthogonal Translation for Site-Specific Installation of Post-translational Modifications
Q Gan, C Fan - Chemical Reviews, 2024 - ACS Publications
Post-translational modifications (PTMs) endow proteins with new properties to respond to
environmental changes or growth needs. With the development of advanced proteomics …
environmental changes or growth needs. With the development of advanced proteomics …
Functional analysis of protein post‐translational modifications using genetic codon expansion
Post‐translational modifications (PTMs) of proteins not only exponentially increase the
diversity of proteoforms, but also contribute to dynamically modulating the localization …
diversity of proteoforms, but also contribute to dynamically modulating the localization …
Recent development of genetic code expansion for posttranslational modification studies
Nowadays advanced mass spectrometry techniques make the identification of protein
posttranslational modifications (PTMs) much easier than ever before. A series of proteomic …
posttranslational modifications (PTMs) much easier than ever before. A series of proteomic …
Chemical biology approaches for studying posttranslational modifications
A Yang, K Cho, HS Park - RNA biology, 2018 - Taylor & Francis
Posttranslational modification (PTM) is a key mechanism for regulating diverse protein
functions, and thus critically affects many essential biological processes. Critical for …
functions, and thus critically affects many essential biological processes. Critical for …
New Strategies for Probing the Biological Functions of Protein Post-translational Modifications in Mammalian Cells with Genetic Code Expansion
Conspectus Protein post-translational modification (PTM) is a major mechanism for
functional diversification of the human genome and plays a crucial role in almost every …
functional diversification of the human genome and plays a crucial role in almost every …
Genetically incorporating two distinct post-translational modifications into one protein simultaneously
S Venkat, J Sturges, A Stahman, C Gregory… - ACS synthetic …, 2018 - ACS Publications
Post-translational modifications (PTMs) play important roles in regulating a variety of
biological processes. To facilitate PTM studies, the genetic code expansion strategy has …
biological processes. To facilitate PTM studies, the genetic code expansion strategy has …
[HTML][HTML] Deciphering post-translational modification codes
Post-translational modifications (PTMs) occur on nearly all proteins. Many domains within
proteins are modified on multiple amino acid sidechains by diverse enzymes to create a …
proteins are modified on multiple amino acid sidechains by diverse enzymes to create a …
Posttranslational chemical mutagenesis methods to insert posttranslational modifications into recombinant proteins
O Harel, M Jbara - Molecules, 2022 - mdpi.com
Posttranslational modifications (PTMs) dramatically expand the functional diversity of the
proteome. The precise addition and removal of PTMs appears to modulate protein structure …
proteome. The precise addition and removal of PTMs appears to modulate protein structure …
Applications of genetic code expansion in studying protein post-translational modification
J Chen, YH Tsai - Journal of Molecular Biology, 2022 - Elsevier
Various post-translational modifications can naturally occur on proteins, regulating the
activity, subcellular localization, interaction, or stability of the proteins. However, it can be …
activity, subcellular localization, interaction, or stability of the proteins. However, it can be …
dbPTM in 2022: an updated database for exploring regulatory networks and functional associations of protein post-translational modifications
Protein post-translational modifications (PTMs) play an important role in different cellular
processes. In view of the importance of PTMs in cellular functions and the massive data …
processes. In view of the importance of PTMs in cellular functions and the massive data …