Intensive adherence counselling for HIV‐infected individuals failing second‐line antiretroviral therapy in Johannesburg, South Africa

MP Fox, R Berhanu, K Steegen… - Tropical Medicine & …, 2016 - Wiley Online Library
Objective In resource‐limited settings, where genotypic drug resistance testing is rarely
performed and poor adherence is the most common reason for treatment failure …

High rate of virological re-suppression among patients failing second-line antiretroviral therapy following enhanced adherence support: A model of care in Khayelitsha …

DB Garone, K Conradie, G Patten, M Cornell… - Southern African journal …, 2013 - ajol.info
Objective. To describe and evaluate the outcomes of a support programme for patients with
virological failure while receiving second-line antiretroviral therapy (ART) in South Africa …

Implementation of an intensive adherence intervention in patients with second-line antiretroviral therapy failure in four west African countries with little access to …

SP Eholie, R Moh, A Benalycherif, D Gabillard… - The Lancet …, 2019 - thelancet.com
Background The decision about whether to switch to third-line antiretroviral therapy (ART) in
patients with treatment failure on second-line therapy is difficult in settings with little access …

[HTML][HTML] Predictors of switch to and early outcomes on third-line antiretroviral therapy at a large public-sector clinic in Johannesburg, South Africa

D Evans, K Hirasen, R Berhanu, G Malete, P Ive… - AIDS Research and …, 2018 - Springer
Background While efficacy data exist, there are limited data on the outcomes of patients on
third-line antiretroviral therapy (ART) in sub-Saharan Africa in actual practice. Being able to …

When patients fail UNAIDS' last 90 ‐ the “failure cascade” beyond 90‐90‐90 in rural Lesotho, Southern Africa: a prospective cohort study

ND Labhardt, I Ringera, TI Lejone… - Journal of the …, 2017 - Wiley Online Library
Introduction: HIV‐infected individuals on first‐line antiretroviral therapy (ART) in resource‐
limited settings who do not achieve the last “90”(viral suppression) enter a complex care …

Adherence is not a barrier to successful antiretroviral therapy in South Africa

C Orrell, DR Bangsberg, M Badri, R Wood - Aids, 2003 - journals.lww.com
Objective: to determine adherence of an indigent African HIV-infected cohort initiating
antiretroviral therapy (ART); to identify predictors of incomplete adherence (< 95%) and …

[HTML][HTML] Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes …

C Orrell, K Cohen, R Leisegang, DR Bangsberg… - AIDS Research and …, 2017 - Springer
Background Incomplete adherence to antiretroviral therapy (ART) results in virologic failure
and resistance. It remains unclear which adherence measure best predicts these outcomes …

Patterns of adherence to antiretroviral therapy and HIV drug resistance over time in the S tratall ANRS 12110/ESTHER trial in C ameroon

M Meresse, L March, C Kouanfack, RC Bonono… - HIV …, 2014 - Wiley Online Library
Objectives The emergence of HIV drug resistance is a crucial issue in A frica, where second‐
line antiretroviral therapy (ART) is limited, expensive and complex. We assessed the …

Effectiveness of interventions for unstable patients on antiretroviral therapy in South Africa: results of a cluster‐randomised evaluation

MP Fox, SJS Pascoe, AN Huber… - Tropical Medicine & …, 2018 - Wiley Online Library
Background As loss from HIV care is an ongoing challenge globally, interventions are
needed for patients who don't achieve or maintain ART stability. The 2015 South African …

[HTML][HTML] Long-term efficacy of first line antiretroviral therapy in Indian HIV-1 infected patients: a longitudinal cohort study

U Neogi, E Heylen, A Shet, S Chandy, R Shamsunder… - PloS one, 2013 - journals.plos.org
Background Short term efficacy of combination antiretroviral therapy (cART) in resource-
constrained settings is comparable to that found in western studies. However, long term data …