INTRODUCTION Neuromodulators, such as dopamine, norepinephrine, or serotonin, exert
powerful control over neural circuit dynamics that give rise to diverse neural function and …

Genetically encoded dopamine sensors based on green fluorescent protein (GFP) enable
high-resolution imaging of dopamine dynamics in behaving animals. However, these GFP …

The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …

Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological
and pathological processes. A longstanding yet largely unmet goal is to measure DA …

Dopamine (DA) plays multiple roles in a wide range of physiological and pathological
processes via a large network of dopaminergic projections. To dissect the spatiotemporal …

Neurotransmission operates on a millisecond timescale but is changed by normal
experience or neuropathology over days to months. Despite the importance of long-term …

The neuronal coding of stimulus-to-action sequences is believed to involve the release of
dopamine (DA) and norepinephrine (NE). The electrochemical similarity of these …

Many debilitating neuropsychiatric and neurodegenerative disorders are characterized by
dopamine neurotransmitter dysregulation. Monitoring subsecond dopamine release …

We demonstrate a technique for mapping brain activity that combines molecular specificity
and spatial coverage using a neurotransmitter sensor detectable by magnetic resonance …

Few tools exist to visualize and manipulate neurons that are targets of neuromodulators. We
present i Tango, a light-and ligand-gated gene expression system based on a light-inducible …