The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Materials that enhance bone regeneration have a wealth of potential clinical applications
from the treatment of nonunion fractures to spinal fusion. The use of porous material …

The successful regeneration of bone tissue to replace areas of bone loss in large defects or
at load‐bearing sites remains a significant clinical challenge. Over the past few decades …

Bone tissue engineering (BTE) aims to develop strategies to regenerate damaged or
diseased bone using a combination of cells, growth factors, and biomaterials. This article …

Bone disorders are of significant concern due to increase in the median age of our
population. Traditionally, bone grafts have been used to restore damaged bone. Synthetic …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

A significant challenge in the current orthopedics is the development of suitable
osteobiologic materials that can replace the conventional allografts, autografts, and …

Key features of bone tissue structure and composition are capable of directing cellular
behavior toward the generation of new bone tissue. Bone tissue, as well as materials …

Despite its intrinsic ability to regenerate form and function after injury, bone tissue can be
challenged by a multitude of pathological conditions. While innovative approaches have …