Drug-induced demyelinating neuropathies

N Niimi, S Takaku, H Yako, K Sango - Myelin: Basic and clinical advances, 2019 - Springer
A large variety of drugs have been reported to cause peripheral neuropathies as dose-
limiting adverse effects; however, most of them primarily affect axons and/or neuronal cell …

Involvement of oxidative stress and impaired lysosomal degradation in amiodarone‐induced schwannopathy

N Niimi, H Yako, M Tsukamoto… - European Journal of …, 2016 - Wiley Online Library
Amiodarone hydrochloride (AMD), an anti‐arrhythmic agent, has been shown to cause
peripheral neuropathy; however, its pathogenesis remains unknown. We examined the toxic …

[HTML][HTML] Recent topics on the mechanisms of immunosuppressive therapy-related neurotoxicities

W Zhang, N Egashira, S Masuda - International journal of molecular …, 2019 - mdpi.com
Although transplantation procedures have been developed for patients with end-stage
hepatic insufficiency or other diseases, allograft rejection still threatens patient health and …

Drug-induced neurological disorders

RJM Lane, PA Routledge - Drugs, 1983 - Springer
When a patient presents with a neurological or neuromuscular disorder, it is essential to
consider drugs as a possible cause. Drugs can affect virtually any part of the neuraxis and …

Nutraceuticals against neurodegeneration: a mechanistic insight

VP Dadhania, PP Trivedi, A Vikram… - Current …, 2016 - ingentaconnect.com
The mechanisms underlying neurodegenerative disorders are complex and multifactorial;
however, accumulating evidences suggest few common shared pathways. These common …

Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis

E Wallström, P Diener, Å Ljungdahl, M Khademi… - Journal of the …, 1996 - Elsevier
Memantine, a clinically employed drug with N-methyl-d-aspartate (NMDA) receptor
antagonistic effects, dose-dependently ameliorates neurological deficits in Lewis rat …

Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models

S Sugama, T Takenouchi, BP Cho… - … & Allergy-Drug …, 2009 - ingentaconnect.com
Microglia has been demonstrated to play critical roles in various neurodegenerative
disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's …

Axonal degeneration in chemotherapy-induced peripheral neurotoxicity: clinical and experimental evidence

SB Park, A Cetinkaya-Fisgin, AA Argyriou… - Journal of Neurology …, 2023 - jnnp.bmj.com
Multiple pathological mechanisms are involved in the development of chemotherapy-
induced peripheral neurotoxicity (CIPN). Recent work has provided insights into the …

Neurodegeneration

S Przedborski - Neuroimmune Pharmacology, 2008 - Springer
An examination of the literature indicates that since 1982 the term neurodegeneration
appears in the title of over 1280 indexed publications. Neurodegeneration is a mentioned …

[HTML][HTML] Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …