Protective effects of garlic extract against hematological alterations, immunosuppression, hepatic oxidative stress, and renal damage induced by cyclophosphamide in …

AM El-Sebaey, FM Abdelhamid, OA Abdalla - Environmental Science and …, 2019 - Springer
Cyclophosphamide is an alkylating agent widely used as anticancer drug, reported to exert
cytotoxic effects attributed to oxidative stress. Therefore, this study aimed to explore the …

Cyclophosphamide instigated hepatic-renal oxidative/inflammatory stress aggravates immunosuppressive indoleamine 2, 3-dioxygenase in male rats: Abatement by …

AP Ebokaiwe, DO Obasi, RCC Njoku, S Osawe… - Toxicology, 2021 - Elsevier
The hepatic-renal toxicity associated with cyclophosphamide (CYP) treatment in both
animals and humans have been reported. Quercetin, a dietary flavonoid, is known to elicit …

Evaluation of sub-chronic chlorpyrifos poisoningon immunological and biochemical changes in ratsand protective effect of eugenol

IA Elelaimy, HM Ibrahim, FRA Ghaffar… - Journal of Applied …, 2012 - japsonline.com
Chlorpyrifos (CPF) is one of the most widely used organophosphorus (OP) insecticides until
2000 when the United States Environmental Protection Agency restricted some of its …

The effect of natural antioxidants in cyclophosphamide-induced hepatotoxicity: Role of Nrf2/HO-1 pathway

IO Sherif - International immunopharmacology, 2018 - Elsevier
Hepatotoxicity induced by cyclophosphamide (Cyclo) is a major concern in clinical practice.
This study was designed to investigate the possible cytoprotective effect of natural …

Ameliorative effect of carob pods extract (Ceratonia siliqua L.) against cyclophosphamide induced alterations in bone marrow and spleen of rats

SA Abd Elhalim, HM Sharada, I Abulyazid… - Journal of Applied …, 2017 - japsonline.com
Cyclophosphamide (CYP) belongs to the anticancer drugs that exhibit potentially life-
threatening effects on the immune and hematopoietic systems. The study aimed to assess …

Protective effect of arbutin against cyclophosphamide-induced oxidative stress, inflammation, and hepatotoxicity via Nrf2/HO-1 pathway in rats

RS Alruhaimi - Environmental Science and Pollution Research, 2023 - Springer
Cyclophosphamide (CP) is a potent anticancer drug widely employed in chemotherapy
against various types of cancer. However, CP leads to toxicity to non-targeted organs …

[HTML][HTML] Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats

M Saoudi, R Badraoui, F Rahmouni… - Frontiers in …, 2021 - frontiersin.org
This study is aimed to elucidate the possible antioxidant and protective effects of Artemisia
campestris essential oil (ACEO) against the deleterious effects of chlorpyrifos (CPF) in rats …

Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy …

C Caglayan, Y Temel, FM Kandemir, S Yildirim… - … Science and Pollution …, 2018 - Springer
Cyclophosphamide (CP) is a common chemotherapeutic agent that is effective against a
wide variety of tumors. The associated hepatotoxicity and nephrotoxicity, however, limit its …

[HTML][HTML] Protective effect of elaeagnus angustifolia L. Fruit hydroalcoholic extract on cyclophosphamide-induced nephrotoxicity in mice

M Goudarzi, M Esmaeilizadeh, M Dolatshahi… - Shiraz E-Medical …, 2018 - brieflands.com
Background: Cyclophosphamide (CP) is one of the most popular bifunctional alkylating
agents, which is utilized in the treatment of numerous cancer diseases and has toxic side …

[HTML][HTML] Cyclophosphamide-induced hepatotoxicity in wistar rats: the modulatory role of gallic acid as a hepatoprotective and chemopreventive phytochemical

AA Oyagbemi, OT Omobowale… - … journal of preventive …, 2016 - journals.lww.com
Background: Gallic acid (GA) is an endogenous plant phenol known to have antioxidant,
free radical scavenging ability, anti-inflammatory, anti-cancer, and anti-fungal properties …