Sodium and potassium and the pathogenesis of hypertension

K Stolarz-Skrzypek, A Bednarski, D Czarnecka… - Current hypertension …, 2013 - Springer
The evidence relating blood pressure to salt intake in humans originates from population
studies and randomized clinical trials of interventions on dietary salt intake. Estimates from …

Reducing salt intake for prevention of cardiovascular disease—times are changing

K Stolarz-Skrzypek, JA Staessen - Advances in chronic kidney disease, 2015 - Elsevier
The evidence relating blood pressure to salt intake in humans originates from population
studies and randomized clinical trials of interventions on dietary salt intake. Estimates from …

Dietary salt reduction in hypertension—What is the evidence and why is it still controversial?

GS Chrysant, S Bakir, S Oparil - Progress in cardiovascular diseases, 1999 - Elsevier
The link between sodium intake and hypertension remains controversial because of
inconsistency between early epidemiologic studies, which showed a strong positive …

Dietary salt restriction and blood pressure in clinical trials

DT Lackland, BM Egan - Current hypertension reports, 2007 - Springer
Dietary salt has long been recognized as a major factor affecting blood pressure such that
sodium intake is a component of lifestyle modification guidelines for control of high blood …

Salt, blood pressure, and human health

MH Alderman - Hypertension, 2000 - Am Heart Assoc
The positive relation of sodium intake and blood pressure, first recognized a century ago,
has been well established in ecological, epidemiological, and experimental human studies …

Salt and hypertension: is salt dietary reduction worth the effort?

TM Frisoli, RE Schmieder, T Grodzicki… - The American journal of …, 2012 - Elsevier
In numerous epidemiologic, clinical, and experimental studies, dietary sodium intake has
been linked to blood pressure, and a reduction in dietary salt intake has been documented …

Salt and blood pressure: time to challenge

B Altun, M Arici - Cardiology, 2005 - karger.com
Hypertension is a worldwide epidemic and its control is costly, but still inadequate. The
mechanisms underlying the development of primary hypertension remain elusive. Several …

High salt intake and cardiovascular disease: is there a connection?

GS Chrysant - Nutrition, 2000 - Elsevier
Several epidemiologic studies in the past have demonstrated a positive association
between high salt intake and the incidence of hypertension. 1, 2 Dahl1 found an almost …

Modest salt reduction lowers blood pressure in isolated systolic hypertension and combined hypertension

FJ He, ND Markandu, GA MacGregor - Hypertension, 2005 - Am Heart Assoc
Many randomized trials have shown that a reduction in salt intake lowers blood pressure in
hypertensive individuals. However, few have looked at the effects according to hypertension …

Sodium and potassium in the pathogenesis of hypertension

HJ Adrogué, NE Madias - New England journal of medicine, 2007 - Mass Medical Soc
This review examines epidemiologic, physiological, and molecular evidence that the
interplay between sodium and potassium is central to the development of hypertension. The …