Personal medicine aims to provide tailor-made diagnostics and treatments and has been
emerged as a promising but challenging strategy during the last years. This includes the …

Cell penetrating peptides (CPPs) offer great potential to deliver therapeutic molecules to
previously inaccessible intracellular targets. However, many CPPs are inefficient and often …

Cell-penetrating peptides (CPPs) have found numerous applications in biology and
medicine since the first synthetic cell-permeable sequence was identified two decades ago …

The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …

The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …

The main problem of therapeutic efficiency lies in the crossing of cellular membranes.
Therefore, significant effort is being made to develop agents which can cross these barriers …

Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …

The increasing popularity of peptides and proteins targeted therapeutics is primarily
attributed to their inherent advantages, such as precise targeting and the reduction of side …

The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Twenty years ago, the discovery of peptides able to cross cellular membranes launched a
novel field in molecular delivery based on these non-invasive vectors, most commonly …