BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer

C Kuang, X Fu, Y Hua, W Shuai, Z Ye, Y Li… - Cell death & …, 2017 - nature.com
Concurrent/adjuvant cisplatin-based chemoradiotherapy is regarded as the standard of
treatment for locoregionally advanced nasopharyngeal carcinoma (NPC). However, patients …

Overexpression of BST2 is associated with nodal metastasis and poorer prognosis in oral cavity cancer

KH Fang, HK Kao, LM Chi, Y Liang, SC Liu… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis Bone marrow stromal cell antigen 2 (BST2) was one of the proteins
that were found to be related to tumor metastasis in our previous proteomic study. Now we …

TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling

T Xu, Y Yang, Z Chen, J Wang, X Wang… - Journal of Experimental …, 2023 - Springer
Background Drug resistance limits the treatment effect of cisplatin-based chemotherapy in
head and neck squamous cell carcinoma (HNSCC), and the underlying mechanism is not …

Blockage of SSRP1/Ets-1/Pim-3 signalling enhances chemosensitivity of nasopharyngeal carcinoma to docetaxel in vitro

J Ai, W Li, R Zeng, Z Xie, H Liu, M Hou, G Tan - Biomedicine & …, 2016 - Elsevier
Nasopharyngeal carcinoma (NPC) is a rare cancer in most parts of the world, but is
prevalent in South China area. Besides, therapeutic outcome is still unsatisfactory for …

BEX 3 contributes to cisplatin chemoresistance in nasopharyngeal carcinoma

W Gao, JZH Li, SQ Chen, CY Chu, JYW Chan… - Cancer …, 2017 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) can develop cisplatin‐resistant phenotype. Research
has revealed that enriched in cancer stem cell population is involved in developing cisplatin …

Parallel genome-wide RNAi screens identify lymphocyte-specific protein tyrosine kinase (LCK) as a targetable vulnerability of cell proliferation and chemoresistance in …

K Liew, GQS Yu, LJW Pua, LZ Wong, SY Tham, LW Hii… - Cancer letters, 2021 - Elsevier
Despite recent in advances in the management of nasopharyngeal carcinoma (NPC),
development of targeted therapy remains challenging particularly in patients with recurrent …

[HTML][HTML] IAP-1 promoted cisplatin resistance in nasopharyngeal carcinoma via inhibition of caspase-3-mediated apoptosis

X Miao, Z Deng, S Wang, H Weng… - American journal of …, 2021 - ncbi.nlm.nih.gov
Recurrent/metastatic nasopharyngeal carcinoma (NPC) is known for having a poor
prognosis due to its unfavorable response to chemoradiotherapy. However, the specific …

[HTML][HTML] C-terminal binding protein‑2 mediates cisplatin chemoresistance in esophageal cancer cells via the inhibition of apoptosis

H Shi, Y Mao, Q Ju, Y Wu, W Bai… - International …, 2018 - spandidos-publications.com
Abstract C-terminal binding protein‑2 (CtBP2) is a transcriptional co-repressor that is
associated with tumorigenesis and tumor progression. It has been reported to predict a poor …

BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling …

F Shan, S Shen, X Wang… - … Journal of Oncology, 2023 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is one of the main types of head and neck squamous
cell carcinoma. Although progress has been made in treating OSCC, it remains a threat to …

Upregulation of THBS1 is Related to Immunity and Chemotherapy Resistance in Gastric Cancer

X Zhang, T Huang, Y Li, H Qiu - International journal of general …, 2021 - Taylor & Francis
Purpose Thrombospondin 1 (THBS1) is an endogenous inhibitor of angiogenesis, but it also
promotes tumor invasion, metastasis, and immune response in the tumor environment …