Objectives The objectives of this study were to assess the clinical characteristics, predictive
factors, and practical algorithms of paradoxical reactions (PRs), specifically paradoxical …

Abstract Background Paradoxical reactions (PRs) are defined as the occurrence during
biologic therapy of a pathological condition that usually responds to these drugs. Objectives …

Background Biological agents that contain substances affecting the immune system are
increasingly being used to treat chronic inflammatory systemic diseases. Aside from the …

Paradoxical reaction (PR) occurs when a drug elicits a reaction contrary to what was
expected. To clarify the clinical features and genetic background of individuals susceptible …

Research Letters 471 226 articles with 391 cases were eligible, with 303 containing
outcomes of interest (Supplementary Fig 1, available via Mendeley at https://data. mendeley …

Biologic drugs, which are molecules designed to act on specific immune system targets,
have been shown to be very effective in treating various dermatological, rheumatological …

The growing availability of target therapies for psoriasis (biologicals) has dramatically
changed the prognosis of the disease. Currently, the therapeutic goal is represented by a …

Abstract Today, anti‐12/IL23, anti‐IL17, and anti‐IL23 provide more efficacious and/or safer
treatment options for psoriasis. Though, anti‐TNF remains a gold standard in the therapy of …

The definition of paradoxical psoriasis (PP) encompasses 2 main scenarios, namely,(i) new-
onset psoriasis in patients treated for a different disease and (ii) worsening as well as …

DEAR EDITOR, Biological drugs have become a common therapy for psoriasis and psoriatic
arthritis (PsA). A paradoxical worsening of psoriasis has been reported in some patients …