Exploring the potentiality of natural products from essential oils as inhibitors of odorant-binding proteins: A structure-and ligand-based virtual screening approach to …
KS da Costa, JM Galúcio, CHS da Costa… - ACS …, 2019 - ACS Publications
Odorant-binding proteins (OBPs) are the main olfactory proteins of mosquitoes, and their
structures have been widely explored to develop new repellents. In the present study, we …
structures have been widely explored to develop new repellents. In the present study, we …
Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking
In this work we report a fast and efficient virtual screening protocol for discovery of novel
bioinspired synthetic mosquito repellents with lower volatility and, in all likelihood, increased …
bioinspired synthetic mosquito repellents with lower volatility and, in all likelihood, increased …
Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents
Insect odorant binding proteins (OBPs) are the first components of the olfactory system to
encounter and bind attractant and repellent odors emanating from various sources for …
encounter and bind attractant and repellent odors emanating from various sources for …
The crystal structure of the AgamOBP1• Icaridin complex reveals alternative binding modes and stereo-selective repellent recognition
CE Drakou, KE Tsitsanou, C Potamitis… - Cellular and Molecular …, 2017 - Springer
Abstract Anopheles gambiae Odorant Binding Protein 1 in complex with the most widely
used insect repellent DEET, was the first reported crystal structure of an olfactory …
used insect repellent DEET, was the first reported crystal structure of an olfactory …
Vitex negundo L. Essential Oil: Odorant Binding Protein Efficiency Using Molecular Docking Approach and Studies of the Mosquito Repellent
Simple Summary Malaria fever kills millions of people annually in the tropical and
subtropical countries of Africa and Asia. Because there is no effective vaccine, malaria …
subtropical countries of Africa and Asia. Because there is no effective vaccine, malaria …
[HTML][HTML] Applications of molecular modeling in the design of new insect repellents targeting the odorant binding protein of Anopheles gambiae
RS Affonso, AP Guimarães, AA Oliveira… - Journal of the Brazilian …, 2013 - SciELO Brasil
Mosquitoes are responsible for conveying various diseases caused by viruses, parasites
and helminthes. Considering the cost and complexity of the treatment of these diseases, the …
and helminthes. Considering the cost and complexity of the treatment of these diseases, the …
[HTML][HTML] Probing insect odorant receptors with their cognate ligands: insights into structural features
Odorant receptors (ORs) are essential for insect survival in the environment and thus are
ideal molecular targets for the design of insect-inspired modern green chemicals to control …
ideal molecular targets for the design of insect-inspired modern green chemicals to control …
Odorant receptors and odorant-binding proteins as insect pest control targets: a comparative analysis
Recently, two alternative targets in insect periphery nerve system have been explored for
environmentally-friendly approaches in insect pest management, namely odorant-binding …
environmentally-friendly approaches in insect pest management, namely odorant-binding …
Different binding properties of two general-odorant binding proteins in Athetis lepigone with sex pheromones, host plant volatiles and insecticides
XQ Zhang, Q Yan, LL Li, JW Xu, D Mang… - Pesticide biochemistry …, 2020 - Elsevier
Athetis lepigone (Alep) is a polyphagous pest native to Europe and Asia that has
experienced major outbreaks in the summer maize area of China since 2011 and has …
experienced major outbreaks in the summer maize area of China since 2011 and has …
Structure of an Odorant-Binding Protein from the Mosquito Aedes aegypti Suggests a Binding Pocket Covered by a pH-Sensitive “Lid”
Background The yellow fever mosquito, Aedes aegypti, is the primary vector for the viruses
that cause yellow fever, mostly in tropical regions of Africa and in parts of South America …
that cause yellow fever, mostly in tropical regions of Africa and in parts of South America …