Chemical mixtures and multiple stressors: same but different?

RB Schäfer, M Jackson… - Environmental …, 2023 - Wiley Online Library
Ecosystems are strongly influenced by multiple anthropogenic stressors, including a wide
range of chemicals and their mixtures. Studies on the effects of multiple stressors have …

[HTML][HTML] Modeling the synergistic effects of toxicant mixtures

M Liess, S Henz, N Shahid - Environmental Sciences Europe, 2020 - Springer
Background Toxicants often occur simultaneously. Some combinations show synergistic
combined effects that go far beyond what is predicted with current effect models. Up until …

Ecotoxicology–how to assess the impact of toxicants in a multi-factorial environment?

H Segner - Multiple stressors: a challenge for the future, 2007 - Springer
Ecotoxicology assesses the fate of contaminants in the environment and contaminant effects
on constituents of the biosphere. With respect to effects assessment, current ecotoxicology …

[图书][B] Multiple stressors: a challenge for the future

C Mothersill, I Mosse, C Seymour - 2007 - books.google.com
Ecotoxiclogical risk from multiple stressors covers any situation where org-isms are exposed
to a combination of environmental stressors. These include physical and chemical pollutants …

[图书][B] Chemical mixtures and combined chemical and nonchemical stressors: exposure, toxicity, analysis, and risk

CV Rider, JE Simmons - 2018 - Springer
All people are exposed to complex and dynamic mixtures of chemicals and nonchemical
stressors throughout their lives. Understanding how these combined exposures impact …

Mixture toxicity revisited from a toxicogenomic perspective

R Altenburger, S Scholz… - … science & technology, 2012 - ACS Publications
The advent of new genomic techniques has raised expectations that central questions of
mixture toxicology such as for mechanisms of low dose interactions can now be answered …

Advancing understanding and prediction in multiple stressor research through a mechanistic basis for null models

RB Schäfer, JJ Piggott - Global Change Biology, 2018 - Wiley Online Library
Global environmental change is driven by multiple anthropogenic stressors. Conservation
and restoration require understanding the individual and joint action of these stressors to …

A framework for predicting impacts on ecosystem services from (sub) organismal responses to chemicals

VE Forbes, CJ Salice, B Birnir… - Environmental …, 2017 - Wiley Online Library
Protection of ecosystem services is increasingly emphasized as a risk‐assessment goal, but
there are wide gaps between current ecological risk‐assessment endpoints and potential …

Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures

DJ Spurgeon, OAH Jones, JLCM Dorne… - Science of the total …, 2010 - Elsevier
Environmental mixtures of chemicals constitute a prevalent issue in ecotoxicology and the
development of new methods to reduce the uncertainties associated with their ecological …

Refocusing multiple stressor research around the targets and scales of ecological impacts

BI Simmons, PSA Blyth, JL Blanchard… - Nature Ecology & …, 2021 - nature.com
Ecological communities face a variety of environmental and anthropogenic stressors acting
simultaneously. Stressor impacts can combine additively or can interact, causing synergistic …