Abdominal aortic aneurysm: novel mechanisms and therapies

FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …

Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' management

J Golledge, PE Norman - Current opinion in cardiology, 2009 - journals.lww.com
Pathophysiology of abdominal aortic aneurysm relevant to imp... : Current Opinion in Cardiology
Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' …

Novel insight into the pathobiology of abdominal aortic aneurysm and potential future treatment concepts

N Diehm, F Dick, T Schaffner, J Schmidli… - Progress in …, 2007 - Elsevier
The patient with abdominal aortic aneurysm (AAA) commonly is a nondiabetic, white man
with a history of smoking. Moreover, AAA represents a leading cause of death in elderly men …

Abdominal aortic aneurysm: pathogenesis and implications for management

J Golledge, J Muller, A Daugherty… - … , and vascular biology, 2006 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) affects approximately 5% of elderly men and is
responsible for a significant number of deaths in Western Countries. At present surgery by …

Pathogenesis of abdominal aortic aneurysm: an update and look toward the future

JJ Grange, V Davis, BT Baxter - Cardiovascular surgery, 1997 - Elsevier
To date, aneurysm research has been primarily descriptive, reiterating the complex nature of
the disease process. Enhanced by the convergence of matrix biochemistry, cell biology and …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

Review of current theories for abdominal aortic aneurysm pathogenesis

IM Nordon, RJ Hinchliffe, PJ Holt, IM Loftus… - …, 2009 - journals.sagepub.com
Atherosclerotic plaques are a feature of abdominal aortic aneurysms (AAAs).
Atherosclerosis and AAA appear to share similar risk factors. These observations have led to …

Current concepts in the pathogenesis of abdominal aortic aneurysm

G Ailawadi, JL Eliason, GR Upchurch - Journal of vascular surgery, 2003 - jvascsurg.org
Abdominal aortic aneurysms (AAAs) are a significant medical problem with a high mortality.
The primary diagnostic code for AAA accounts for approximately 150,000 inpatient hospital …

[HTML][HTML] Experimental models of abdominal aortic aneurysms

JC Tsui - The open cardiovascular medicine journal, 2010 - ncbi.nlm.nih.gov
Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic
aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of …