Streptococcus pneumoniae is the most common cause of community-acquired pneumonia,
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …

Following usage of the pneumococcal conjugate vaccine in children, the incidence of
invasive pneumococcal disease declined in both children and adults (reflecting herd …

Invasive pneumococcal infection remains a leading global cause of morbidity and mortality
in young children. In developed nations, a substantial decrease in the incidence of IPD has …

Background. A 7-valent conjugate pneumococcal vaccine (PCV7) was introduced in 2000.
Methods. We determined serotypes and assessed antimicrobial susceptibility of 1235 …

Background: After the widespread use of the 7-valent pneumococcal conjugate vaccine,
replacement serotypes have emerged. Serogroups 15 and 33 have emerged as nonvaccine …

Background: Because the heptavalent pneumococcal conjugate vaccine has reduced
vaccine-type invasive pneumococcal disease (IPD) in children, a greater proportion of IPD is …

Objective. Despite immunization with heptavalent pneumococcal conjugate vaccine (PCV7),
the rising prevalence of antibiotic resistance makes Streptococcus pneumoniae a continuing …

Background. Streptococcus pneumoniae (pneumococcus) caused approximately 44000 US
invasive pneumococcal disease (IPD) cases in 2008. Antibiotic nonsusceptibility …

Streptococcus pneumoniae is the most common cause of both pneumonia overall and fatal
pneumonia. Antibiotic resistance has developed worldwide and is most frequent in …

Background: The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the
United States in February 2000. The PROTEKT US study evaluated serotype distribution …