Facile preparation and properties of porous poly (vinyl alcohol)/trehalose/nano-clay hydrogels with high mechanical strength for potential application in bone tissue …

C Xiang, Q Zhang, Z Guo, Z Wang, W Chen, X Li… - European Polymer …, 2023 - Elsevier
Among various biomaterials, hydrogels are considered as the most attractive tissue
engineering material due to their resemblances to extracellular matrix. However, due to the …

A porous hydrogel with high mechanical strength and biocompatibility for bone tissue engineering

C Xiang, X Zhang, J Zhang, W Chen, X Li… - Journal of Functional …, 2022 - mdpi.com
Polyvinyl alcohol (PVA) hydrogels are considered to be ideal materials for tissue
engineering due to their high water content, low frictional behavior, and good …

Tough physically crosslinked poly (vinyl alcohol)-based hydrogels loaded with collagen type I to promote bone regeneration in vitro and in vivo

C Xiang, Z Wang, Q Zhang, Z Guo, X Li, W Chen… - International Journal of …, 2024 - Elsevier
Abstract Poly (vinyl alcohol)(PVA) hydrogels exhibit great potential as ideal biomaterials for
tissue engineering, owing to their non-toxicity, high water content, and strong …

Vascularized nanocomposite hydrogel mechanically reinforced by polyelectrolyte-modified nanoparticles

Q Zhang, Q Pei, J Yang, S Guo, A Yang… - Journal of Materials …, 2022 - pubs.rsc.org
Vascularization plays an important role in the initial stage of triggering bone defect repair.
The combination of bioactive small molecule drugs and biomaterials has been a powerful …

Fabrication and characterization of porous, degradable, biocompatible poly (vinyl alcohol)/tannic acid/gelatin/hyaluronic acid hydrogels with good mechanical …

C Xiang, Z Guo, Z Wang, J Zhang, W Chen… - Journal of …, 2023 - Taylor & Francis
At present, articular cartilage repair and regeneration remain still one of the most concerned
problems due to its poor self-healing capacity. Among the tissue engineering materials …

Macroporous polyvinyl alcohol-tannic acid hydrogel with high strength and toughness for cartilage replacement

H Li, J Li, T Li, C Wu, W Zhang - Journal of Materials Science, 2022 - Springer
Polyvinyl alcohol (PVA) hydrogels as alternative materials for biomedical applications have
attracted extensive attention. However, the development of bioactive hydrogel with …

Progress and prospects of nanocomposite hydrogels in bone tissue engineering

C Du, W Huang - Nanocomposites, 2022 - Taylor & Francis
Hydrogels are hydrophilic polymers with high flexibility and elasticity, and are widely used in
the field of bone tissue engineering. However, their low toughness and insufficient …

Synthesis of mechanically stiff and bioactive hybrid hydrogels for bone tissue engineering applications

A Kumar, KM Rao, SS Han - Chemical Engineering Journal, 2017 - Elsevier
A 3D microenvironment is essential for the cell adhesion and proliferation necessary to
achieve the desired regeneration of damaged tissues or organs. To this end, hydrogels may …

Mechanically improved porous hydrogels with polysaccharides via polyelectrolyte complexation for bone tissue engineering

M Suneetha, KM Rao, SS Han - International journal of biological …, 2020 - Elsevier
Bone tissue engineering aims to design mechanically improved macroporous hydrogels
with fibrous topologies using polysaccharides that can provide an appropriate …

A nanoparticle reinforced microporous methacrylated silk fibroin hydrogel to promote bone regeneration

R Wang, X He, Z Chen, S Su, J Bai, H Liu… - Biomaterials Science, 2024 - pubs.rsc.org
Natural polymer-based hydrogels have been widely applied in bone tissue engineering due
to their excellent biocompatibility and outstanding ability of drug encapsulation. However …