Plasmodium parasites are transmitted by Anopheles mosquitoes to the mammalian host and
actively infect hepatocytes after passive transport in the bloodstream to the liver. In their …

Autophagy plays an important role in the defence against intracellular pathogens. However,
some microorganisms can manipulate this host cell pathway to their advantage. In this study …

The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-
mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) …

Recent years have witnessed a great gain in knowledge regarding parasite–host cell
interactions during Plasmodium liver stage development. It is now an accepted fact that a …

Eukaryotic cells can employ autophagy to defend themselves against invading pathogens.
Upon infection by Plasmodium berghei sporozoites, the host hepatocyte targets the invader …

Liver stage Plasmodium parasites reside in a parasitophorous vacuole (PV) that associates
with lysosomes. It has previously been shown that these organelles can have beneficial as …

The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and
undergoes obligatory development within a parasitophorous vacuole in hepatocytes before …

The obligate intracellular liver stage of the Plasmodium parasite represents a bottleneck in
the parasite life cycle and remains a promising target for therapeutic intervention. During this …

The causative agent of malaria, Plasmodium, replicates inside a membrane-bound
parasitophorous vacuole (PV), which shields this intracellular parasite from the cytosol of the …

Fluorescence and light microscopy are important tools in the history of natural science.
However, the resolution of microscopes is limited by the diffraction of light. One possible …