Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

Melanin, a major pigment in mammalian skin, is known to protect the skin against harmful
effects of ultraviolet (UV) irradiation, oxidative stress, and DNA damage. The accumulation …

Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Tyrosinase is a copper‐containing enzyme, which is widely distributed in microorganisms,
animals and plants and is a key enzyme in melanin biosynthesis, involved in determining …

Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in …

Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Ethnopharmacological relevance Tyrosinase, the key rate-limiting enzyme for
melanogenesis, is one of the main targets for skin senescence and some pigmented skin …

Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …