The role of astrocytes in synapse loss in Alzheimer's disease: a systematic review
LA Hulshof, D van Nuijs, EM Hol… - Frontiers in Cellular …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
worldwide. One pathological feature of progressing AD is the loss of synapses. This is the …
worldwide. One pathological feature of progressing AD is the loss of synapses. This is the …
The role of glial cells and synapse loss in mouse models of Alzheimer's disease
S Ziegler-Waldkirch… - Frontiers in cellular …, 2018 - frontiersin.org
Synapse loss has detrimental effects on cellular communication, leading to network
disruptions within the central nervous system (CNS) such as in Alzheimer's disease (AD) …
disruptions within the central nervous system (CNS) such as in Alzheimer's disease (AD) …
[HTML][HTML] The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Y Yu, R Chen, K Mao, M Deng, Z Li - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impacts a
substantial number of individuals globally. Despite its widespread prevalence, there is …
substantial number of individuals globally. Despite its widespread prevalence, there is …
Pathological phenotypes of astrocytes in Alzheimer's disease
J Kim, ID Yoo, J Lim, JS Moon - Experimental & Molecular Medicine, 2024 - nature.com
Astrocytes are involved in various processes in the central nervous system (CNS). As the
most abundant cell type in the CNS, astrocytes play an essential role in neuronal …
most abundant cell type in the CNS, astrocytes play an essential role in neuronal …
Dysregulation of astrocyte–neuronal communication in Alzheimer's disease
C Nanclares, AM Baraibar, A Araque… - International journal of …, 2021 - mdpi.com
Recent studies implicate astrocytes in Alzheimer's disease (AD); however, their role in
pathogenesis is poorly understood. Astrocytes have well-established functions in supportive …
pathogenesis is poorly understood. Astrocytes have well-established functions in supportive …
The contribution of astrocytes to Alzheimer's disease
AM Birch - Biochemical Society Transactions, 2014 - portlandpress.com
Astrocytes were historically classified as supporting cells; however, it is becoming
increasingly clear that they actively contribute to neuronal functioning under normal and …
increasingly clear that they actively contribute to neuronal functioning under normal and …
Reactive astrocytes as drug target in Alzheimer's disease
BT Assefa, AK Gebre, BM Altaye - BioMed research …, 2018 - Wiley Online Library
Alzheimer's disease is a neurodegenerative disease characterized by deposition of
extracellular amyloid‐β, intracellular neurofibrillary tangles, and loss of cortical neurons …
extracellular amyloid‐β, intracellular neurofibrillary tangles, and loss of cortical neurons …
Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
The many faces of astrocytes in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease and is the most
common cause of dementia in an aging population. The majority of research effort has …
common cause of dementia in an aging population. The majority of research effort has …
When astrocytes become harmful: functional and inflammatory responses that contribute to Alzheimer's disease
E Avila-Muñoz, C Arias - Ageing research reviews, 2014 - Elsevier
A growing body of research suggests that astrocytes play roles as contributors to the
pathophysiology of Alzheimer's disease (AD). Several lines of evidence propose that …
pathophysiology of Alzheimer's disease (AD). Several lines of evidence propose that …
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