Matrine and Oxymatrine: evaluating the gene mutation potential using in silico tools and the bacterial reverse mutation assay (Ames test)

BC Fischer, Y Musengi, J König, B Sachse… - …, 2024 - academic.oup.com
The quinolizidine alkaloids matrine and its N-oxide oxymatrine occur in plants of the genus
Sophora. Recently, matrine was sporadically detected in liquorice products. Morphological …

Analysis and occurrence of matrine in liquorice raw materials-Exclusion of its application as pesticide

J Schultz, M Raters, M Wittig, B Christall… - Food Additives & …, 2022 - Taylor & Francis
ABSTRACT A quick and selective analytical method was developed employing LC-MS/MS
for the quantitation of matrine. This is known to be a natural ingredient of Sophora ssp. and …

Identification of glutathione S-transferase inhibiting natural products from Matricaria chamomilla and biotransformation studies on oxymatrine and harmine

C Iverson - 2010 - mspace.lib.umanitoba.ca
This thesis describes the results obtained from the phytochemical analysis of Matricaria
chamomilla, and the microbial transformation of oxymatrine (85) and harmine (87), as …

Matrine and oxymatrine in corroborant plant extracts and fertilizers: HPLC/MS-MS method development and single-laboratory validation

L Sabatino, M Scarangella, F Lazzaro… - … Science and Health …, 2015 - Taylor & Francis
A reversed phase high-performance liquid chromatographic method (HPLC/MS-MS) has
been developed and validated for detection of alkaloids matrine and oxymatrine in fertilizer …

Antimitotic effects of the biopesticide oxymatrine

D Akdeniz, A Özmen - Caryologia, 2011 - Taylor & Francis
Biopesticides offer a more sustainable solution to pest control than synthetic alternatives.
Naturally plant products, called secondary metabolites include thousands of alkaloids …

The advances in bioactivities, mechanisms of action and structural optimizations of matrine and its derivatives

J Xu, M Lv, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Matrine, a tetracyclo-quinolizidine alkaloid, is isolated from the industrial crop plant Sophora
flavescens. Due to a wide range of pharmacological and agricultural properties, the …

MARSI: metabolite analogues for rational strain improvement

JGR Cardoso, AA Zeidan, K Jensen… - …, 2018 - academic.oup.com
Metabolite analogues (MAs) mimic the structure of native metabolites, can competitively
inhibit their utilization in enzymatic reactions, and are commonly used as selection tools for …

[HTML][HTML] Research progress of natural matrine compounds and synthetic matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

[HTML][HTML] Synthesis, characterization and in vitro biological evaluation of two matrine derivatives

X Cheng, J Ye, H He, Z Liu, C Xu, B Wu, X Xiong… - Scientific Reports, 2018 - nature.com
Matrine is a traditional Chinese medicine and botanical pesticide with broad biological
activities, including pharmacological and agricultural activities. In present work, two matrine …

Mutagenicity and genotoxicity studies of arruva, an R, R-monatin salt isomer

PL Casterton, WA Brathwaite, CM Crincoli - Food and chemical toxicology, 2014 - Elsevier
Arruva, the R, R-isomer of monatin (sodium/potassium 2R, 4R-2-amino-4-carboxy-4-hydroxy-
5-(3-indolyl) pentanoate), an intense sweetener originally identified in root bark of the South …