Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Single-cell RNA sequencing (scRNA-seq) is a tool for studying gene expression at the
single-cell level that has been widely used due to its unprecedented high resolution. In the …

Cancer has become one of the greatest threats to human health, and new technologies are
urgently needed to further clarify the mechanisms of cancer so that better detection and …

Single-cell RNA sequencing (scRNA-seq), a technology that analyzes transcriptomes of
complex tissues at single-cell levels, can identify differential gene expression and epigenetic …

Unlike population-level approaches, single-cell RNA sequencing enables transcriptomic
analysis of an individual cell. Through the combination of high-throughput sequencing and …

Almost all biomedical research to date has relied upon mean measurements from cell
populations, however it is well established that what it is observed at this macroscopic level …

Single cell sequencing (SCS) can be harnessed to acquire the genomes, transcriptomes
and epigenomes from individual cells. Next generation sequencing (NGS) technology is the …

The emerging single-cell RNA-Seq (scRNA-Seq) technology holds the promise to
revolutionize our understanding of diseases and associated biological processes at an …

Tumors are complex ecosystems in which heterogeneous cancer cells interact with their
microenvironment composed of diverse immune, endothelial, and stromal cells. Cancer …

As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …