Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Diagnostic value of highly-sensitive chimerism analysis after allogeneic stem cell transplantation

L Sellmann, K Rabe, I Bünting, E Dammann… - Bone marrow …, 2018 - nature.com
Conventional analysis of host chimerism (HC) frequently fails to detect relapse before its
clinical manifestation in patients with hematological malignancies after allogeneic stem cell …

Significance of chimerism in hematopoietic stem cell transplantation: new variations on an old theme

F Khan, A Agarwal, S Agrawal - Bone marrow transplantation, 2004 - nature.com
The main goal of post-transplantation monitoring in hematopoietic stem cell transplantation
(HSCT) is to predict negative events, such as disease relapse, graft rejection and graft …

Use of chimerism analysis after allogeneic stem cell transplantation: Belgian guidelines and review of the current literature

A Delie, A Verlinden, K Beel, D Deeren… - Acta Clinica …, 2021 - Taylor & Francis
Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative
treatment option in both adult and pediatric patients with malignant and non-malignant …

Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) …

JR Clark, SD Scott, AL Jack, H Lee… - British journal of …, 2015 - Wiley Online Library
Analysis of short tandem repeats (STR) is the predominant method for post‐transplant
monitoring of donor engraftment. It can enable early detection of disease relapse, level of …

[HTML][HTML] Chimerism monitoring techniques after hematopoietic stem cell transplantation: an overview of the last 15 years of innovations

P Tozzo, A Delicati, R Zambello, L Caenazzo - Diagnostics, 2021 - mdpi.com
Chimerism analysis is a well-established method for monitoring the state of hematopoietic
stem cell transplantation (HSCT) over time by analyzing peripheral blood or bone marrow …

Strategies and clinical implications of chimerism diagnostics after allogeneic hematopoietic stem cell transplantation

C Thiede, M Bornhäuser, G Ehninger - Acta haematologica, 2004 - karger.com
Abstract Analysis of donor chimerism has become a routine method for the documentation of
engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years …

A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

How and when should we monitor chimerism after allogeneic stem cell transplantation?

P Bader, D Niethammer, A Willasch… - Bone marrow …, 2005 - nature.com
Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

Detection of impending graft rejection and relapse by lineage-specific chimerism analysis

T Lion - Bone Marrow and Stem Cell Transplantation, 2007 - Springer
Molecular surveillance of hematopoietic chimerism has become part of the routine
diagnostic program in patients after allogeneic stem cell transplantation. Chimerism testing …