Design, synthesis and in vitro cytotoxicity studies of novel β-carbolinium bromides

POV Reddy, S Mishra, MP Tantak, K Nikhil… - Bioorganic & medicinal …, 2017 - Elsevier
A series of novel β-carbolinium bromides has been synthesized from easily accessible β-
carbolines and 1-aryl-2-bromoethanones. The newly synthesized compounds were …

Synthesis and cytotoxic activities of 1-benzylidine substituted β-carboline derivatives

R Cao, W Yi, Q Wu, X Guan, M Feng, C Ma… - Bioorganic & Medicinal …, 2008 - Elsevier
A series of new β-carboline derivatives, bearing a benzylidine substituent at position-1, has
been prepared and evaluated in vitro against a panel of human cell lines. The N2 …

Synthesis and biological evaluation of a novel class of β-carboline derivatives

H Chen, P Gao, M Zhang, W Liao, J Zhang - New Journal of Chemistry, 2014 - pubs.rsc.org
In this study, several novel β-carboline derivatives, 1-(4-hydroxy-3-methoxyphenyl)-β-
carboline-3-carboxyl-Trp-Trp-AA-OBzl compounds, were designed and synthesized as …

Synthesis and biological evaluation of bivalent β-carbolines as potential anticancer agents

H Du, H Gu, N Li, J Wang - MedChemComm, 2016 - pubs.rsc.org
A series of novel bivalent β-carbolines were synthesized and evaluated for their anti-
proliferative activities on a panel of cancer cell lines, apoptosis induction and cell cycle …

Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline–imidazolium salt derivatives

B Zhou, ZF Liu, GG Deng, W Chen, MY Li… - Organic & …, 2016 - pubs.rsc.org
The synthesis of a series of novel N-substituted tetrahydro-β-carboline–imidazolium salt
derivatives is presented. The biological properties of the compounds were evaluated in vitro …

[PDF][PDF] Synthesis and in Vitro Cytotoxic Activity of Some Novel β-Carbolines bearing pyrrol-2-one moiety

SS Kumar, M Mariappan - International Journal of Pharma Sciences and …, 2013 - Citeseer
ABSTRACT β-carboline are reported to have anticancer activities on cultured cancer cell
lines. To further enhance the cytotoxic potency, a series of novel 5-substituted β-carboline …

[HTML][HTML] Design, synthesis and mechanism of action of novel 1, 9-disubstituted β-carboline derivatives as antitumor agents

F Zhao, J Ao, F Zeng, R Cao, X Li - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract A range of novel 1, 9-disubstituted β-carboline derivatives was designed,
synthesized and evaluated as potential anticancer agents. The preliminary study suggested …

Synthesis, Characterization and In vitro Antitumour Activity of Novel Organotin Derivatives of 1,2‐ and 1,7‐Dicarba‐Closo‐dodecaboranes

M Gielen, F Kayser, OB Zhidkova… - Metal‐Based …, 1995 - Wiley Online Library
Several organotin derivatives of 1, 2‐and 1, 7‐dicarba‐closo‐dodecaboranes were
synthesized and characterized by 119Sn Mössbauer, 1H, 13C and 119Sn NMR …

Synthesis and cytotoxic activity of new β-carboline derivatives

A Peduto, V More, P de Caprariis… - Mini Reviews in …, 2011 - ingentaconnect.com
On the basis of harmine and 1-methoxy-canthin-6-one chemical structures, a series of novel
1, 4-disubstituted and 1, 4, 9-trisubstituted β-carbolines and tetracyclic derivatives were …

3-Benzylamino-β-carboline derivatives induce apoptosis through G2/M arrest in human carcinoma cells HeLa S-3

R Ikeda, T Iwaki, T Iida, T Okabayashi, E Nishi… - European journal of …, 2011 - Elsevier
β-Carboline derivatives are known as the lead compounds for anti-tumor agents. To
examine an optimal structure for anti-tumor activity, we synthesized a variety of β-carboline …