Reprogramming energy production from mitochondrial respiration to glycolysis is now
considered a hallmark of cancer. When tumors grow beyond a certain size they give rise to …

Warburg's observation that cancer cells exhibit a high rate of glycolysis even in the presence
of oxygen (aerobic glycolysis) sparked debate over the role of glycolysis in normal and …

Cancer cells reprogram their metabolism to meet the requirement for survival and rapid
growth. One hallmark of cancer metabolism is elevated aerobic glycolysis and reduced …

Metabolic alterations have been observed in many cancer types. The deregulated
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …

Aerobic glycolysis is the process of oxidation of glucose into pyruvate followed by lactate
production under normoxic condition. Distinctive from its anaerobic counterpart (ie glycolysis …

Anomalous increase in glycolytic activity defines one of the key metabolic alterations in
cancer cells. A realization of this feature has led to critical advancements in cancer detection …

The propensity of cancer cells to convert high levels of glucose to lactate through aerobic
glycolysis has been intensively studied in vitro, and is now understood to be a metabolic …

Reprogramming of cellular metabolism is a hallmark of cancers. Cancer cells more readily
use glycolysis, an inefficient metabolic pathway for energy metabolism, even when sufficient …

Altered energy metabolism is a biochemical fingerprint of cancer cells that represents one of
the “hallmarks of cancer”. This metabolic phenotype is characterized by preferential …

Mammalian cells depend on extracellular input for the regulation of growth, proliferation and
survival. Cancer cells evade these requirements, and are able to take up nutrients in a cell …