Importance More than 240 million individuals worldwide are infected with chronic hepatitis B
virus (HBV). Among individuals with chronic HBV infection who are untreated, 15% to 40 …

BACKGROUND & AIMS: The relative efficacies of licensed antiviral therapies for treatment-
naive chronic hepatitis B (CHB) infection in randomized controlled trials have not been …

Since active hepatitis B virus (HBV) replication is the key driver of hepatic necroinflammation
and disease progression, the treatment aim of chronic hepatitis B (CHB) is to suppress HBV …

Aliment Pharmacol Ther 2011; 34: 1145–1158 Summary Background The indications and
endpoints for treatment of chronic hepatitis B continue to evolve. The aim of the therapy for …

Chronic hepatitis B (CHB) virus infection is a global public health problem, affecting more
than 400 million people worldwide. The clinical spectrum is wide, ranging from a subclinical …

Chronic hepatitis B viral (HBV) infection remains a significant global health problem.
Evidence‐based guidelines are needed to help providers determine when treatment should …

Chronic hepatitis B (CHB) continues to be an important public health problem worldwide,
including in the United States. An algorithm for managing CHB was developed by a panel of …

Chronic hepatitis B can currently be medically managed with either pegylated interferon-
alpha (pegIFN-α) or one of the five nucleos (t) ide analog Direct Acting Antivirals (DAAs) that …

The 2009 update of the American Association for the Study of Liver Diseases (AASLD)
Practice Guidelines for Management of Chronic Hepatitis B are now posted online at www …

Background The long‐term goals of therapy for chronic hepatitis B are to reduce serum HBV
DNA to low or undetectable levels and ultimately reduce or prevent the development of …