Vascular pathologies underpin and intertwine autoimmune rheumatic diseases and
cardiovascular conditions, and atherosclerosis is increasingly recognized as the leading …

Vascular inflammation underlies most forms of cardiovascular disease, which remains a
prevalent cause of death among the global population. Advances in the biology of …

Infiltration of leukocyte subsets is a driving force of atherosclerotic lesion growth, and during
the past decade, neutrophils have received growing attention in chronic inflammatory …

Neutrophils constitute the first line of defense in human immunity and can be attracted to
inflamed and infected sites by various chemokines. As essential players in immune …

Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

Neutrophils, as part of the innate immune system, are classically described to be main actors
during the onset of inflammation enforcing rapid neutralisation and clearance of pathogens …

Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …

Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …

Neutrophils are important components of immunity associated with inflammatory responses
against a broad spectrum of pathogens. These cells could be rapidly activated by …

In inflammatory conditions such as RA, the neutrophil has tended to be dismissed as a short-
lived, terminally differentiated, irrelevant bystander cell. However, this is clearly not the case …