Alzheimer's and Parkinson's disease therapies in the clinic

P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …

[HTML][HTML] Advances in developing novel therapeutic strategies for Alzheimer's disease

J Cao, J Hou, J Ping, D Cai - Molecular neurodegeneration, 2018 - Springer
Abstract Alzheimer's Disease (AD), the most prevalent neurodegenerative disease of aging,
affects one in eight older Americans. Nearly all drug treatments tested for AD today have …

New and emerging treatments for Alzheimer's disease

A Corbett, J Smith, C Ballard - Expert Review of Neurotherapeutics, 2012 - Taylor & Francis
Alzheimer's disease (AD) and other dementias represent a significant and increasing clinical
challenge. This review highlights current treatment options for AD and the main focusses of …

[HTML][HTML] Symptomatic and disease-modifying therapy pipeline for Alzheimer's disease: Towards a personalized polypharmacology patient-centered approach

X Morató, V Pytel, S Jofresa, A Ruiz… - International Journal of …, 2022 - mdpi.com
Since 1906, when Dr. Alois Alzheimer first described in a patient “a peculiar severe disease
process of the cerebral cortex”, people suffering from this pathology have been waiting for a …

Nanotechnological applications for the treatment of neurodegenerative disorders

G Modi, V Pillay, YE Choonara, VMK Ndesendo… - Progress in …, 2009 - Elsevier
Nanotechnology employs engineered materials or devices that interact with biological
systems at a molecular level and could revolutionize the treatment of neurodegenerative …

Advances in the treatment of neurodegenerative disorders employing nanotechnology

G Modi, V Pillay, YE Choonara - … of the New York Academy of …, 2010 - Wiley Online Library
Due to limitations posed by the restrictive blood–brain barrier, conventional drug delivery
systems do not provide adequate cyto‐architecture restoration and connection patterns that …

Alzheimer's disease: the right drug, the right time

TE Golde, ST DeKosky, D Galasko - Science, 2018 - science.org
Alzheimer's disease (AD) is an age-associated neurodegenerative disease that is reaching
epidemic proportions as a result of the aging of the world's population. Impressive gains in …

Current perspectives on pharmacotherapy of Alzheimer's disease

K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …

Alzheimer's disease drug development pipeline: 2020

J Cummings, G Lee, A Ritter… - … research & clinical …, 2020 - Wiley Online Library
Introduction Alzheimer's disease (AD) is a growing public health concern affecting millions of
patients worldwide and costing billions of dollars annually. We review the pipeline of drugs …

Current and future treatments in Alzheimer disease: an update

KG Yiannopoulou… - Journal of central …, 2020 - journals.sagepub.com
Disease-modifying treatment strategies for Alzheimer disease (AD) are still under extensive
research. Nowadays, only symptomatic treatments exist for this disease, all trying to …