[HTML][HTML] TRAF3 is required for NF-κB pathway activation mediated by HTLV tax proteins
S Fochi, E Bergamo, M Serena, S Mutascio… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia viruses type 1 (HTLV-1) and type 2 (HTLV-2) share a common
genome organization and expression strategy but have distinct pathological properties …
genome organization and expression strategy but have distinct pathological properties …
[HTML][HTML] HTLV deregulation of the NF-κB pathway: An update on tax and antisense proteins role
S Fochi, S Mutascio, U Bertazzoni, D Zipeto… - Frontiers in …, 2018 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …
Human T-cell leukemia virus type 1 Tax induction of NF-κB involves activation of the IκB kinase α (IKKα) and IKKβ cellular kinases
R Geleziunas, S Ferrell, X Lin, Y Mu… - … and cellular biology, 1998 - Am Soc Microbiol
Tax corresponds to a 40-kDa transforming protein from the pathogenic retrovirus human T-
cell leukemia virus type 1 (HTLV-1) that activates nuclear expression of the NF-κB/Rel family …
cell leukemia virus type 1 (HTLV-1) that activates nuclear expression of the NF-κB/Rel family …
[HTML][HTML] A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells
S Millen, L Meretuk, T Göttlicher, S Schmitt… - Retrovirology, 2020 - Springer
Background Human T-cell leukemia virus type 1 (HTLV-1) infects primarily CD4+ T-
lymphocytes and evoques severe diseases, predominantly Adult T-Cell …
lymphocytes and evoques severe diseases, predominantly Adult T-Cell …
Modulation of nuclear factor-ϰB by human T cell leukemia virus type 1 tax protein: Implications for oncogenesis and inflammation
JM Peloponese, ML Yeung, KT Jeang - Immunologic research, 2006 - Springer
Activation of the nuclear factor kappa B (NF-ϰB) transcription factor family by different
stimuli, such as inflammatory cytokines, stress inducers, or pathogens, results in innate and …
stimuli, such as inflammatory cytokines, stress inducers, or pathogens, results in innate and …
[HTML][HTML] HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways
R Currer, R Van Duyne, E Jaworski, I Guendel… - Frontiers in …, 2012 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …
[HTML][HTML] Highlights on distinctive structural and functional properties of HTLV Tax proteins
MG Romanelli, E Diani, E Bergamo, C Casoli… - Frontiers in …, 2013 - frontiersin.org
Human T cell leukemia viruses (HTLVs) are complex human retroviruses of the
Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 …
Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 …
[HTML][HTML] Regulation of NF-κB by the HTLV-1 Tax protein
The Tax protein encoded by the human T-cell leukemia virus type 1 (HTLV-1) activates viral
gene expression via the ATF/CREB pathway. Tax also induces a variety of cellular genes …
gene expression via the ATF/CREB pathway. Tax also induces a variety of cellular genes …
[HTML][HTML] Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein
M Turci, J Lodewick, G Di Gennaro, AS Rinaldi… - Retrovirology, 2012 - Springer
Abstract Background Retroviruses HTLV-1 and HTLV-2 have homologous genomic
structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell …
structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell …
[HTML][HTML] Mechanisms of oncogenesis by HTLV-1 Tax
The human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …