Methylene blue (MB) is a well-established drug with a long history of use, owing to its
diverse range of use and its minimal side effect profile. MB has been used classically for the …

Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and
oxidative stress, which are important factors contributing to the development of brain …

This paper provides the first review of the memory-enhancing and neuroprotective metabolic
mechanisms of action of methylene blue in vivo. These mechanisms have important …

By restoring mitochondrial function, methylene blue (MB) is an effective neuroprotectant in
many neurological disorders (eg, Parkinson's and Alzheimer's diseases). MB has also been …

Neuroprotective strategies, including free radical scavengers, ion channel modulators, and
anti-inflammatory agents, have been extensively explored in the last 2 decades for the …

Methylene blue (MB) belongs to the phenothiazinium family. It has been used to treat a
variety of human conditions and has beneficial effects on the central nervous system in …

Methylene blue (MB), the first lead chemical structure of phenothiazine and other
derivatives, is commonly used in diagnostic procedures and as a treatment for …

The redox dye methylene blue (MB) is proven to have beneficial effects in various models of
neurodegenerative diseases. Here we investigated the effects of MB (100 nM, 300 nM, and …

The relationship between methylene blue (MB) and Alzheimer's disease (AD) has recently
attracted increasing scientific attention since it has been suggested that MB may slow down …

Methylene blue (MB) phase II clinical trials reported improvements in cognitive functions of
Alzheimer's disease (AD) patients. Regarding MB mechanism of action, its antioxidant and …