Objective. To explore the mechanism of catechol‐O‐methyltransferase (COMT) in tooth
movement pain. Methods. The experimental groups were randomly allocated into the …

Objective: To test the hypothesis that the chemokine ligand 2/chemokine receptor 2
(CCL2/CCR2) signaling pathway plays an important role in pain induced by experimental …

Pain is among the major problems during orthodontic treatment. Recent studies have shown
that central Cyclooxygenase2 (COX2) pathway was involved in several pain models. The …

PURPOSE: Sprague-Dawley rat models of tooth movement were established to investigate
the expression of transient receptor potential vanilloid 1 (TRPV1) and calcitonin gene …

PURPOSE: To establish a Sprague-Dawley rat model of tooth movement, detect the
expression of calcitonin gene-related peptide (calcitonin gene related peptide, CGRP) in …

Objectives To investigate the roles of chemokine (CC motif) ligand 8 (CCL8) in periodontal
ligament during orthodontic tooth movement (OTM). Methods Bioinformatics analyzed 100 …

Aims: To evaluate the association between catechol-O-methyltransferase (COMT) gene
polymorphisms and temporomandibular disorders (TMD), TMD pain, psychosocial …

Neurons in the trigeminal mesencephalic nucleus (Vme) have an axon that branches
peripherally to innervate the orofacial region and projects centrally to the trigeminal motor …

Pain is a sensation generated by an organism as a response to a stimulus able to cause
tissue damage. Thus, pain has a clear evolutional value by promoting the survival of an …

Objectives The aim of this study was to explore the effect of capsaicin on expression patterns
of calcitonin gene-related peptide (CGRP) in the trigeminal ganglion (TG) and trigeminal …