Immunogenicity and tolerance induction in vascularized composite allotransplantation

J Sun, A Adil, F Biniazan, S Haykal - Frontiers in Transplantation, 2024 - frontiersin.org
Vascularized composite allotransplantation (VCA) is the transplantation of multiple tissues
such as skin, muscle, bone, nerve, and vessels, as a functional unit (ie, hand or face) to …

[HTML][HTML] Tolerance induction in vascularized composite allotransplantation—a brief review of preclinical models

L Huelsboemer, M Kauke-Navarro… - Transplant …, 2023 - frontierspartnerships.org
Pre-clinical studies are an obligatory tool to develop and translate novel therapeutic
strategies into clinical practice. Acute and chronic rejection mediated by the recipient's …

Inaugural Issue of VCA-Vascularized Composite Allotransplantation

G Brandacher, DH Sachs, WPA Lee - Vascularized Composite …, 2014 - Taylor & Francis
Vascularized Composite Allotransplantation is an emerging new era in transplant medicine
and has become a viable reconstructive option for patients with extensive tissue defects and …

[HTML][HTML] Immunology of vascularized composite allografts

G Brandacher, DH Sachs… - Clinical and …, 2013 - ncbi.nlm.nih.gov
Over the past decade, vascularized composite allotransplantation (VCA), such as hand and
face transplantation, has become a clinical reality and a viable treatment option for those …

Cellular activation pathways and interaction networks in vascularized composite allotransplantation

L Knoedler, S Knoedler, AC Panayi, CAA Lee… - Frontiers in …, 2023 - frontiersin.org
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …

Tolerance induction strategies in vascularized composite allotransplantation: mixed chimerism and novel developments

DA Leonard, DA McGrouther, JM Kurtz… - Journal of …, 2012 - Wiley Online Library
Since the start of the clinical vascularized composite allotransplantation (VCA) era over a
decade ago this field has witnessed significant developments in both basic and translational …

The need for inducing tolerance in vascularized composite allotransplantation

KV Ravindra, H Xu, LD Bozulic… - Journal of …, 2012 - Wiley Online Library
Successful hand and face transplantation in the last decade has firmly established the field
of vascularized composite allotransplantation (VCA). The experience in VCA has thus far …

Vascularized composite tissue allotransplantation–state of the art

JR Diaz‐Siso, EM Bueno, GC Sisk… - Clinical …, 2013 - Wiley Online Library
Vascularized composite tissue allotransplantation is a viable treatment option for injuries
and defects that involve multiple layers of functional tissue. In the past 15 yr, more than 150 …

Review of the early diagnoses and assessment of rejection in vascularized composite allotransplantation

R Starzl, G Brandacher, WPA Lee… - Journal of …, 2013 - Wiley Online Library
The emerging field of vascular composite allotransplantation (VCA) has become a clinical
reality. Building upon cutting edge understandings of transplant surgery and immunology …

Composite tissue allotransplantation: opportunities and challenges

J Iske, Y Nian, R Maenosono, M Maurer… - Cellular & molecular …, 2019 - nature.com
Vascularized composite allotransplants (VCAs) have unique properties because of diverse
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …