Increasing prevalence of native lowlanders sojourning to high altitudes (> 2,500 m) for
recreational, occupational, military, and competitive reasons has generated increased …

High altitude is an extreme environment that challenges human beings exposed because of
work, recreational activities, or habitat. Exposure to hypobaric hypoxia results in …

To prepare for extremes of heat, cold or low partial pressures of oxygen (O 2), humans can
undertake a period of acclimation or acclimatization to induce environment-specific …

The (patho-) physiological responses to hypoxia are highly heterogeneous between
individuals. In this review, we focused on the roles of sex differences, which emerge as …

Sex differences in physiological responses to various stressors, including exercise, have
been well documented. However, the specific impact of these differences on exposure to …

Cross-adaptation (CA) refers to the successful induction of physiological adaptation under
one environmental stressor (eg, heat), to enable subsequent benefit in another (eg …

The Research Topic “Integrative physiological approaches to understand high altitude
adaptation” showcases pioneering research into the physiological mechanisms that enable …

It is well-established that different altitude training modalities can improve convective oxygen
(O2) transport capacity and physical fitness of athletes (Millet et al., 2010). Exercising in …

Alterations in cardiovascular and respiratory function are extremely important as we ascend
to high altitude since the associated hypoxia leads to tachycardia, increased cardiac output …

ABSTRACT Wyatt, FB. Physiological Responses to Altitude: A Brief Review. JEPonline
2014; 17 (1): 90-96. Hypoxia has been defined as conditions with lower than normal oxygen …