Dysregulation of the placental renin–angiotensin system in human fetal growth restriction

SJ Delforce, ER Lumbers, SJ Ellery, P Murthi… - …, 2019 - rep.bioscientifica.com
Fetal growth restriction (FGR) is a pregnancy complication wherein the fetus fails to reach its
growth potential. The renin–angiotensin system (RAS) is a critical regulator of placental …

The rat placental renin-angiotensin system-a gestational gene expression study

K Vaswani, HW Chan, P Verma, M Dekker Nitert… - Reproductive Biology …, 2015 - Springer
Background The placenta is an essential organ that provides nutrients and oxygen to the
developing fetus and removes toxic waste products from the fetal circulation. Maintaining …

Protein restriction to pregnant rats increases the plasma levels of angiotensin II and expression of angiotensin II receptors in uterine arteries

H Gao, U Yallampalli, C Yallampalli - Biology of Reproduction, 2012 - academic.oup.com
Whether gestational protein restriction affects the renin-angiotensin system (RAS) in uterine
artery remains unknown. In this study, we hypothesized that gestational protein restriction …

The expression and localization of the human placental prorenin/renin-angiotensin system throughout pregnancy: roles in trophoblast invasion and angiogenesis?

KG Pringle, MA Tadros, RJ Callister, ER Lumbers - Placenta, 2011 - Elsevier
The renin-angiotensin system (RAS) is thought to regulate placentation, however, the
expression and localization of RAS pathways in early gestation human placenta is not …

Regulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines

Y Wang, KG Pringle, YX Chen, T Zakar, ER Lumbers - Placenta, 2012 - Elsevier
OBJECTIVES: The renin-angiotensin system (RAS) is implicated in placentation. We
determined which RAS pathways are present in two trophoblast cell lines (HTR-8/SVneo …

The uteroplacental renin-angiotensin system: a review

A Hagemann, AH Nielsen… - Experimental and Clinical …, 1994 - thieme-connect.com
Evidence has accumulated for the existence of local tissue renin-angiotensin systems in the
reproductive tissues. In the ovary the local renin-angiotensin system (RAS) has been shown …

Expression of the renin-angiotensin system in a human placental cell line

N Pan, WL Frome, RA Dart… - Clinical Medicine & …, 2013 - Marshfield Clinic
Background The renin-angiotensin system (RAS) is present in human placental tissue and
participates in regulation of maternal-fetal blood flow during pregnancy. RAS expression in …

Current topic: the uteroplacental renin–angiotensin system

AH Nielsen, KH Schauser, K Poulsen - Placenta, 2000 - Elsevier
The components of the renin–angiotensin system (RAS) are expressed in the uteroplacental
unit. The expression varies between species, probably due to the marked species …

Maternal protein restriction reduces expression of angiotensin I-converting enzyme 2 in rat placental labyrinth zone in late pregnancy

H Gao, U Yallampalli, C Yallampalli - Biology of Reproduction, 2012 - academic.oup.com
Both the systemic and the uteroplacental renin-angiotensin system (RAS) display dramatic
changes during pregnancy. However, whether gestational protein insufficiency affects the …

Effects of circulating and local uteroplacental angiotensin II in rat pregnancy

L Hering, F Herse, N Geusens, S Verlohren… - …, 2010 - Am Heart Assoc
The renin-angiotensin (Ang) system is important during placental development.
Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats …