Multiplex proteomic evaluation in inborn errors with deregulated IgE response

E Scala, S Madonna, D Castiglia, A Scala, E Caprini… - Biomedicines, 2023 - mdpi.com
(1) Background: Atopic dermatitis constitutes one of the most common inflammatory skin
manifestations of the pediatric population. The onset of many inborn errors occurs early in …

Molecular microarray analysis reveals allergen‐and exotoxin‐specific IgE repertoires in children with atopic dermatitis

H Ott, S Weissmantel, LN Kennes… - Journal of the …, 2014 - Wiley Online Library
Background Children suffering from atopic dermatitis frequently show allergen‐specific
sensitization. However, the corresponding IgE‐recognition patterns have not yet been …

Molecular diagnosis of allergy: the pediatric perspective

S Dramburg, PM Matricardi - Frontiers in pediatrics, 2019 - frontiersin.org
In times of “Precision Medicine” it is fundamental to identify the individual disease phenotype
in order to provide an individualized therapy for every patient. This concept is also becoming …

Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients

PM Brunner, A Israel, A Leonard, AB Pavel… - Annals of Allergy …, 2019 - Elsevier
Background Atopic dermatitis (AD) predominantly affects young children, but our
understanding of AD pathogenesis is based on skin and blood samples from long-standing …

Exploring the temporal development of childhood IgE profiles to allergen components

A Önell, L Hjälle, MP Borres - Clinical and translational allergy, 2012 - Springer
Background Children often develop allergies that may or not persist into adulthood.
Although the different allergic symptoms over time have been well documented, the …

[引用][C] Microarray‐based IgE serology improves management of severe atopic dermatitis in two children

E Fedenko, O Elisyutina, O Shtyrbul… - Pediatric Allergy and …, 2016 - Wiley Online Library
To the Editor, Atopic dermatitis (AD) is one of the most common manifestations of IgE-
associated allergy in childhood (1). In the prospective German MAS cohort, it was shown …

Detection of IgE reactivity to a handful of allergen molecules in early childhood predicts respiratory allergy in adolescence

M Wickman, C Lupinek, N Andersson, D Belgrave… - …, 2017 - thelancet.com
Background Sensitization in early childhood may precede respiratory allergy in
adolescence. Methods IgE reactivity against 132 allergen molecules was evaluated using …

Proteomic approaches for identifying new allergens and diagnosing allergic diseases

JM González-Buitrago, L Ferreira, M Isidoro-García… - Clinica Chimica …, 2007 - Elsevier
BACKGROUND: Allergic diseases are (IgE)-mediated hypersensitivity reactions affecting
more than 25% of the world's population. Proteomic technologies have been increasingly …

Profound differences in IgE and IgG recognition of micro‐arrayed allergens in hyper‐IgE syndromes

V Garib, M Ben‐Ali, M Kundi, M Curin, R Yaakoubi… - Allergy, 2022 - Wiley Online Library
Abstract Background The specificities of IgE and IgG for allergen molecules in patients with
inborn errors of immunity (IEI) have not been investigated in detail. Objective To study IgE …

Expression profiling: opportunities and pitfalls and impact on the study and management of allergic diseases

SJ Ono, T Nakamura, M Ohbayashi… - Journal of allergy and …, 2003 - jacionline.org
Eleven years have passed since Liang and Pardee 1 reported gene profiling through
differential display–PCR technology and 8 years since Schena et al 2 reported the profiling …