Neuroticism is a heritable trait composed of separate facets, each conferring different levels
of protection or risk, to health. By examining mitochondrial DNA in 269,506 individuals, we …

Neuroticism is an important risk factor for psychiatric traits, including depression, anxiety,,
and schizophrenia,–. At the time of analysis, previous genome-wide association studies …

Stressful life events are major environmental risk factors for anxiety disorders, although not
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …

Neuroticism is a relatively stable personality trait characterized by negative emotionality (for
example, worry and guilt); heritability estimated from twin studies ranges from 30 to 50 …

Mitochondria is the major site of energy production in cells, therefore, mitochondrial
abnormality may affect functions of organs including the brain, which constantly requires …

Higher scores on the personality trait of neuroticism, the tendency to experience negative
emotions, are associated with worse mental and physical health. Studies examining links …

Background Psychiatric disorders have great health hazards and the exact pathogeny
remains elusive now. We aim to explore the potential interaction effects of mitochondrial …

Neuroticism is a personality trait that describes the tendency to experience negative
emotions. Individual differences in neuroticism are moderately stable across much of the life …

We investigated the relationship between neuroticism and 16 mental and 18 physical traits
using summary results of genome-wide association studies for these traits. LD score …

Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a …