CD4+ Th cells play an important role in the development of rheumatoid arthritis (RA) by
regulating adaptive immune response. As major subsets of CD4+ Th cells, Th17 cells can …

Th17 cells are generally considered to be positive regulators of immune responses because
they produce pro-inflammatory cytokines, including IL-17A, IL-17F, and IL-22. Cytokine …

Helper T (Th) cells play an important role in the pathogenesis of autoimmune diseases,
including rheumatoid arthritis (RA). It has been revealed that Th17 cells can shift to Th1 cells …

Th17 cells are a new subset of CD4+ T cells involved in the clearance of extracellular
pathogens and fungi. Accumulating evidence suggests that Th17 cells and their signature …

Recent work has implicated a novel Th effector cell subset, the Th17 cell subset, in the
development of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) …

Inflammatory T cells are thought to be central to the pathology of autoimmune arthritis. Th17
cells, CD4 T cells that secrete the pro-inflammatory cytokine IL-17 play a critical role in …

Interleukin-17-producing CD4+ T cells (Th17 cells) are the dominant pathogenic cellular
component in autoimmune inflammatory diseases, including autoimmune arthritis. IL-10 …

The Th17 lineage, a lineage of effector CD4+ T cells, is characterized by the production of IL-
17. Expansion of Th17 cells has been implicated in a growing list of autoimmune disorders …

Abstract IL-17A-producing CD4+ T helper cells (Th17) are crucial for the development of
inflammatory and autoimmune diseases and thus are exploited for clinical immunotherapies …

Abstract T helper 17 (Th17) cells are important mediators of immune responses against
extracellular bacteria and fungi, and as such play critical regulatory roles in maintaining …