Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse
targets. However, application of aptamers to the field of amyloid β-protein (Aβ) has been …

Deposition of amyloid-β (Aβ) peptides in the brain is a central event in the pathogenesis of
Alzheimer's disease (AD), which makes Aβ peptides a crucial target for therapeutic …

Aptamers are useful molecular recognition tools in research, diagnostics, and therapy.
Despite promising results in other fields, aptamer use has remained scarce in amyloid …

Alzheimer's disease (AD) is an irreversible neurodegenerative disease, causing profound
social and economic implications. Early diagnosis and treatment of AD have faced great …

Aptamers are oligonucleotides selected from large pools of random sequences based on
their affinity for bioactive molecules and are used in similar ways to antibodies. Aptamers …

Alzheimer's disease (AD) is a progressive, age-dependent, neurodegenerative disorder with
an insidious course that renders its presymptomatic diagnosis difficult1. Definite AD …

Alzheimer's disease is correlated with the deposition of amyloid peptides in the brain of the
patients. The amyloid is thus a major target in the search for novel diagnostic and …

RNA aptamers have garnered attention for diagnostic applications due to their ability to
recognize diverse targets. Oligomers of 42-mer amyloid β-protein (Aβ42), whose …

We have developed a novel functional nucleic acid aptamer to amyloid-β peptide 1–40 (Aβ1–
40) and investigated its potential to detect Aβ peptide fragments in neuropathologically …

Aggregation of amyloid β-peptide (Aβ) is closely related to the pathogenesis of Alzheimer's
disease (AD). Much effort has been devoted to the construction of molecules that suppress …