Emotionally significant experiences tend to be well remembered, and the amygdala has a
pivotal role in this process. But the efficient encoding of emotional memories can become …

The hippocampus and amygdala are important components of the neural circuitry mediating
stress responses. While structural plasticity in the hippocampus may mediate cognitive …

Recent studies have identified major components of the neural system mediating the
classical conditioning of defense or fear responses to sensory stimuli. The pathways involve …

Prolonged and severe stress leads to cognitive deficits, but facilitates emotional behaviour.
Little is known about the synaptic basis for this contrast. Here, we report that in rats …

A key assumption in the study of stress-induced cognitive and neurobiological modifications
is that alterations in hippocampal functioning after stress are due to an excessive activity …

Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …

BACKGROUND: Chronic stress is a major health concern, often leading to depression,
anxiety, or when severe enough, posttraumatic stress disorder. While many studies …

Variations in people's vulnerability to stressful life events may rise from a predated neural
sensitivity as well as from differential neural modifications in response to the event. Because …

The amygdala has long been known to play a key role in supporting memory for emotionally
arousing experiences. For example, classical fear conditioning depends on neural plasticity …

BACKGROUND: A vital component of an organism's response to acute stress is a surge in
vigilance that serves to optimize the detection and assessment of threats to its homeostasis …