MS: a CNS and systematic autoimmune disease
DA Hafler, HL Weiner - Immunology today, 1989 - cell.com
Mu~ e sderosis (MS) is an inflammatory disease which exclusively affects the white matter of
the central nervous system (CNS). Although there is a localized immune response within the …
the central nervous system (CNS). Although there is a localized immune response within the …
Current trends in multiple sclerosis research
BH Waksman - Immunology today, 1981 - cell.com
Byron Waksman discusses existing evidence which suggests that MS occurs in genetically
predisposed individuals mamfesling d@ cts in immune regulation. It appears to be triggered …
predisposed individuals mamfesling d@ cts in immune regulation. It appears to be triggered …
[引用][C] Immunologic mechanisms and therapy in multiple sclerosis
DA HAFLER, HL WEINER - Immunological reviews, 1995 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS)
myelin characterized by focal T-cell and macrophage infiltrates that lead to demyelination …
myelin characterized by focal T-cell and macrophage infiltrates that lead to demyelination …
Immunology of multiple sclerosis
M Sospedra, R Martin - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract Multiple sclerosis (MS) develops in young adults with a complex predisposing
genetic trait and probably requires an inciting environmental insult such as a viral infection …
genetic trait and probably requires an inciting environmental insult such as a viral infection …
The role of the humoral immune system in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE)
T Ziemssen, F Ziemssen - Autoimmunity reviews, 2005 - Elsevier
The pathogenic events in multiple sclerosis (MS) that result in immune cell infiltration,
multifocal demyelination and axonal loss have been focused by the strong impact of the …
multifocal demyelination and axonal loss have been focused by the strong impact of the …
T cells in multiple sclerosis and inflammatory central nervous system diseases.
DA Hafler, HL Weiner - Immunological reviews, 1987 - europepmc.org
Using murine monoclonal antibodies to mark total T cells, we have found rapid migration of
T cells into the CSF in progressive multiple sclerosis patients, suggesting that the ongoing …
T cells into the CSF in progressive multiple sclerosis patients, suggesting that the ongoing …
Immunological basis of systemic sclerosis
JP Zuber, F Spertini - Rheumatology, 2006 - academic.oup.com
Systemic sclerosis (SSc) is a disease of unknown aetiology characterized by excessive and
often progressive fibrosis in skin and multiple internal organs, an aberrant immune activation …
often progressive fibrosis in skin and multiple internal organs, an aberrant immune activation …
Immunology of multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS)
leading to demyelination, axonal damage, and progressive neurologic disability. The …
leading to demyelination, axonal damage, and progressive neurologic disability. The …
Multiple sclerosis: a pivotal role for the T cell in lesion development
CS Raine - Neuropathology and applied neurobiology, 1991 - Wiley Online Library
The recognition of an increasing number of similarities between the immunologic anomalies
associated with multiple sclerosis (MS) and the T cell‐mediated demyelinating model …
associated with multiple sclerosis (MS) and the T cell‐mediated demyelinating model …
Immunopathogenesis of multiple sclerosis: the role of T cells
G Martino, HP Hartung - Current opinion in neurology, 1999 - journals.lww.com
Multiple sclerosis is considered to be an autoimmune disease that results from aberrant
immune responses to central nervous system antigens. T cells are considered to be crucial …
immune responses to central nervous system antigens. T cells are considered to be crucial …