Hyaluronic acid and its derivatives in drug delivery and imaging: Recent advances and challenges
Hyaluronic acid (HA) is a biodegradable, biocompatible, nontoxic, and non-immunogenic
glycosaminoglycan used for various biomedical applications. The interaction of HA with the …
glycosaminoglycan used for various biomedical applications. The interaction of HA with the …
Recent progresses in the development of hyaluronic acid-based nanosystems for tumor-targeted drug delivery and cancer imaging
HJ Cho - Journal of pharmaceutical investigation, 2020 - Springer
Background Hyaluronic acid (HA) has been widely used as one of major components of
nanocarriers for cancer imaging and therapy. HA possesses hydrophilic and anionic …
nanocarriers for cancer imaging and therapy. HA possesses hydrophilic and anionic …
Hyaluronic acid conjugates as vectors for the active targeting of drugs, genes and nanocomposites in cancer treatment
Hyaluronic acid (HA) is a naturally-occurring glycosaminoglycan and a major component of
the extracellular matrix. Low levels of the hyaluronic acid receptor CD44 are found on the …
the extracellular matrix. Low levels of the hyaluronic acid receptor CD44 are found on the …
Hyaluronan as tunable drug delivery system
The hyaluronan (HA) polymer is an important macromolecule of extracellular matrix with
remarkable structure and functions: it is a linear and unbranched polymer without sulphate …
remarkable structure and functions: it is a linear and unbranched polymer without sulphate …
Recent developments in hyaluronic acid-based nanomedicine for targeted cancer treatment
Introduction: Hyaluronic acid (HA) has emerged as a promising applicant for the tumor-
targeted delivery of various therapeutic agents. Because of its biocompatibility …
targeted delivery of various therapeutic agents. Because of its biocompatibility …
Hyaluronic acid for anticancer drug and nucleic acid delivery
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
Hyaluronic acid: A review on its biology, aspects of drug delivery, route of administrations and a special emphasis on its approved marketed products and recent …
Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …
Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives
Hyaluronic acid (HA) is a biodegradable, biocompatible, non-toxic, non-immunogenic and
non-inflammatory linear polysaccharide, which has been used for various medical …
non-inflammatory linear polysaccharide, which has been used for various medical …
Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer
The therapeutic efficacy of most drugs is greatly depends on their ability to cross the cellular
barrier and reach their intracellular target sites. To transport the drugs effectively through the …
barrier and reach their intracellular target sites. To transport the drugs effectively through the …
Hyaluronic acid-based theranostic nanomedicines for targeted cancer therapy
Hyaluronic acid (HA) is a natural mucopolysaccharide and has many useful advantages,
including biocompatibility, non-immunogenicity, chemical versatility, non-toxicity …
including biocompatibility, non-immunogenicity, chemical versatility, non-toxicity …