[HTML][HTML] Damage-associated molecular patterns in trauma

B Relja, WG Land - European journal of trauma and emergency surgery, 2020 - Springer
Abstract In 1994, the “danger model” argued that adaptive immune responses are driven
rather by molecules released upon tissue damage than by the recognition of “strange” …

[HTML][HTML] Danger signals in trauma

B Relja, K Mörs, I Marzi - European journal of trauma and emergency …, 2018 - Springer
This review summarizes a short list of currently discussed trauma-induced danger-
associated molecular patterns (DAMP). Due to the bivalent character and often pleiotropic …

[HTML][HTML] Use of DAMPs and SAMPs as therapeutic targets or therapeutics: a note of caution

WG Land - Molecular Diagnosis & Therapy, 2020 - Springer
This opinion article discusses the increasing attention paid to the role of activating damage-
associated molecular patterns (DAMPs) in initiation of inflammatory diseases and …

Immune response to traumatic injury: harmony and discordance of immune system homeostasis

A Osuka, H Ogura, M Ueyama… - Acute Medicine & …, 2014 - Wiley Online Library
Trauma remains one of the leading causes of death worldwide. Traumatic injury disrupts
immune system homeostasis and may predispose patients to opportunistic infections and …

[HTML][HTML] DAMPs from cell death to new life

E Vénéreau, C Ceriotti, ME Bianchi - Frontiers in immunology, 2015 - frontiersin.org
Our body handles tissue damage by activating the immune system in response to
intracellular molecules released by injured tissues [damage-associated molecular patterns …

Damage-associated molecular patterns and the systemic immune consequences of severe thermal injury

PB Comish, D Carlson, R Kang… - The journal of immunology, 2020 - journals.aai.org
Thermal injury is often associated with a proinflammatory state resulting in serious
complications. After a burn, the innate immune system is activated with subsequent immune …

[HTML][HTML] Trauma-induced damage-associated molecular patterns-mediated remote organ injury and immunosuppression in the acutely ill patient

M Vourc'h, A Roquilly, K Asehnoune - Frontiers in immunology, 2018 - frontiersin.org
Trauma is one of the leading causes of death and disability in the world. Multiple trauma or
isolated traumatic brain injury are both indicative of human tissue damage. In the early …

[HTML][HTML] The role of damage-associated molecular patterns (DAMPs) in human diseases: part II: DAMPs as diagnostics, prognostics and therapeutics in clinical …

WG Land - Sultan Qaboos University Medical Journal, 2015 - ncbi.nlm.nih.gov
This article is the second part of a review that addresses the role of damage-associated
molecular patterns (DAMPs) in human diseases by presenting examples of traumatic …

Damage associated molecular pattern molecules

MT Lotze, A Deisseroth, A Rubartelli - Clinical immunology, 2007 - Elsevier
Members of the Federation of Clinical Immunology Societies are invited to attend an exciting
meeting on damage-associated molecular pattern molecules [DAMPs] in acute and chronic …

DAMPs activating innate immune responses in sepsis

JW Kang, SJ Kim, HI Cho, SM Lee - Ageing research reviews, 2015 - Elsevier
Sepsis refers to the deleterious and non-resolving systemic inflammatory response of the
host to microbial infection and is the leading cause of death in intensive care units. The …