Calcium sensors in neuronal function and dysfunction

RD Burgoyne, N Helassa… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Calcium signaling in neurons as in other cell types can lead to varied changes in cellular
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …

The diversity of calcium sensor proteins in the regulation of neuronal function

HV McCue, LP Haynes… - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Calcium signaling in neurons as in other cell types mediates changes in gene expression,
cell growth, development, survival, and cell death. However, neuronal Ca2+ signaling …

[HTML][HTML] Sense and specificity in neuronal calcium signalling

RD Burgoyne, LP Haynes - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Abstract Changes in the intracellular free calcium concentration ([Ca 2+] i) in neurons
regulate many and varied aspects of neuronal function over time scales from microseconds …

Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling

RD Burgoyne - Nature Reviews Neuroscience, 2007 - nature.com
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …

The use of transgenic mouse models to reveal the functions of Ca2+ buffer proteins in excitable cells

B Schwaller - Biochimica et Biophysica Acta (BBA)-General Subjects, 2012 - Elsevier
BACKGROUND: Cytosolic Ca2+ buffers are members of the large family of Ca2+-binding
proteins and are essential components of the Ca2+ signaling toolkit implicated in the precise …

Understanding the physiological roles of the neuronal calcium sensor proteins

RD Burgoyne, LP Haynes - Molecular brain, 2012 - Springer
Calcium signalling plays a crucial role in the control of neuronal function and plasticity.
Changes in neuronal Ca 2+ concentration are detected by Ca 2+-binding proteins that can …

Neuronal Ca2+-sensor proteins: multitalented regulators of neuronal function

RD Burgoyne, DW O'Callaghan, B Hasdemir… - Trends in …, 2004 - cell.com
Many aspects of neuronal activity are regulated by Ca 2+ signals. The transduction of
temporally and spatially distinct Ca 2+ signals requires the action of Ca 2+-sensor proteins …

Calcium binding proteins in the brain.

MR Celio - Archivio Italiano di Anatomia e di embriologia. Italian …, 1989 - europepmc.org
It is astonishing how a single ion, Ca++, can give rise to so many intracellular effects. The
current explanation is that various combinations and permutations of a repertoire of calcium …

Genetically encoded calcium indicators as probes to assess the role of calcium channels in disease and for high-throughput drug discovery

JJ Bassett, GR Monteith - Advances in Pharmacology, 2017 - Elsevier
Abstract The calcium ion (Ca 2+) is an important signaling molecule implicated in many
cellular processes, and the remodeling of Ca 2+ homeostasis is a feature of a variety of …

[引用][C] Regulation of calcium homoeostasis in neurons: the role of calcium-binding proteins

RJ Miller - Biochemical Society Transactions, 1995 - portlandpress.com
Calcium has a tremendous number of secondmessenger roles to play in neurons. These
range from the control of neuronal excitability, transmitter release and metabolism to the …