Cell penetrating peptides (CPPs) can deliver cell-impermeable therapeutic cargos into cells.
In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis …

Cell-penetrating peptides (CPPs) have long held great promise for the manipulation of living
cells for therapeutic and research purposes. They allow a wide array of biomolecules from …

Cell-penetrating peptides (CPPs) are capable of delivering membrane-impermeable
cargoes (including small molecules, peptides, proteins, nucleic acids, and nanoparticles) …

The cell membrane poses a substantial hurdle to the use of pharmacologically active
biomacromolecules that are not per se actively translocated into cells. An appealing …

Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Cell-penetrating peptides (CPPs) are short peptides of less than 30 amino acids that are
able to penetrate cell membranes and translocate different cargoes into cells. The only …

The growing number of reports on the effective cargo delivery by cell-penetrating peptides
(CPPs) has extensively widened our knowledge about the mechanisms involved in CPP …

The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …

Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …