The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold
Nuclear proteins are often given a concise title that captures their function, such as
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …
Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation
Proteins of the Drosophila behavior/human splicing (DBHS) family include mammalian
SFPQ (PSF), NONO (p54nrb), PSPC1, and invertebrate NONA and Hrp65. DBHS proteins …
SFPQ (PSF), NONO (p54nrb), PSPC1, and invertebrate NONA and Hrp65. DBHS proteins …
The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation
M Lee, A Sadowska, I Bekere, D Ho… - Nucleic acids …, 2015 - academic.oup.com
Abstract SFPQ,(aka PSF), is a human tumor suppressor protein that regulates many
important functions in the cell nucleus including coordination of long non-coding RNA …
important functions in the cell nucleus including coordination of long non-coding RNA …
Rbfox2 controls autoregulation in RNA-binding protein networks
M Jangi, PL Boutz, P Paul, PA Sharp - Genes & development, 2014 - genesdev.cshlp.org
The tight regulation of splicing networks is critical for organismal development. To maintain
robust splicing patterns, many splicing factors autoregulate their expression through …
robust splicing patterns, many splicing factors autoregulate their expression through …
PSF: nuclear busy‐body or nuclear facilitator?
CA Yarosh, JR Iacona, CS Lutz… - Wiley Interdisciplinary …, 2015 - Wiley Online Library
PTB‐associated splicing factor (PSF) is an abundant and essential nucleic acid‐binding
protein that participates in a wide range of gene regulatory processes and cellular response …
protein that participates in a wide range of gene regulatory processes and cellular response …
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity
The Trithorax group (TrxG) is composed of diverse, evolutionary conserved proteins that
form chromatin-associated complexes accounting for epigenetic transcriptional memory …
form chromatin-associated complexes accounting for epigenetic transcriptional memory …
Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and …
B Dong, DS Horowitz, R Kobayashi… - Nucleic acids …, 1993 - academic.oup.com
While searching for a human homolog of the S. cerevlslae splicing factor PRP18, we found a
polypeptide that reacted strongly with antibodies against PRP18. We purified this …
polypeptide that reacted strongly with antibodies against PRP18. We purified this …
From head to toes: the multiple facets of Sox proteins
M Wegner - Nucleic acids research, 1999 - academic.oup.com
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found
throughout the animal kingdom. They are involved in the regulation of such diverse …
throughout the animal kingdom. They are involved in the regulation of such diverse …
[HTML][HTML] Prep1, a novel functional partner of Pbx proteins
J Berthelsen, V Zappavigna, F Mavilio, F Blasi - The EMBO journal, 1998 - embopress.org
The human transcription factor, UEF3, is important in regulating the activity of the urokinase
plasminogen activator (uPA) gene enhancer. The UEF3 DNA target site is a regulatory …
plasminogen activator (uPA) gene enhancer. The UEF3 DNA target site is a regulatory …
[HTML][HTML] DUSPs, to MAP kinases and beyond
CY Huang, TH Tan - Cell & bioscience, 2012 - Springer
Phosphatases are important regulators of intracellular signaling events, and their functions
have been implicated in many biological processes. Dual-specificity phosphatases …
have been implicated in many biological processes. Dual-specificity phosphatases …