Age is a major risk factor for developing metabolic diseases such as obesity and diabetes.
There is an unprecedented rise in obesity and type 2 diabetes in recent decades. A …

The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Kisspeptin, a neuropeptide hormone, has been firmly established as a key regulator of the
hypothalamic–pituitary–gonadal axis and mammalian reproductive behaviour. In recent …

While kisspeptin was initially found to function as a metastasis suppressor, after
identification of its receptor KISS1R and their expression profiles in tissues such as the …

Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and
appetite in humans. Materials and methods In 15 healthy men (age: 25.2±1.1 years; BMI …

their wild-type counterparts, however, they were still obese—possibly owing to observed
reductions in respiratory rate, energy expenditure and locomotor activity. The results …

To evaluate if plasma kisspeptin concentrations are associated with insulin secretion, as
suggested by recent in vitro studies, independently of confounders. 261 nondiabetic …

Apart from the well-established role of kisspeptin (Kp) in the regulation of reproductive
functions, recent data described its action in the control of metabolism. Of particular interest …

Kisspeptin was initially identified as a metastasis suppressor. Shortly after the initial
discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with …

Kisspeptin is a hypothalamic protein critical for neuroendocrine control of pubertal
development and fertility and is modulated by nutritional signals. Kisspeptin has been …