Aging is accompanied by remodeling of the immune system. With time, this leads to a
decline in immune efficacy, resulting in increased vulnerability to infectious diseases …

Aging is a natural physiological process that features various and variable challenges,
associated with loss of homeostasis within the organism, often leading to negative …

Ageing is characterized by immunosenescence and the progressive decline in immunity in
association with an increased frequency of infections and chronic disease. This complex …

The immune system is the most important protective physiological system of the organism. It
has many connections with other systems and is, in fact, often considered as part of the …

Prolonged life expectancy in the 20th century has been one of humankind's greatest
triumphs. However, the substantial increase in the human life span has ushered in a new …

Major advances in preventing, delaying, or curing individual pathologies are responsible for
an increasingly long life span in the developed parts of our planet, and indeed reaching …

During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Introduction Aging causes several changes in the immune system, although immune aging
is strongly influenced by individual immunological history, as well as genetic and …

Abstract On April 7, 8, 2009 a Symposium entitled" Pathophysiology of Successful and
Unsuccessful Ageing" took place in Palermo, Italy. Here, the lectures of G. Pawelec, D. Dunn …

Cellular senescence is a critical part of human anti-tumor defence; however, the
accumulation of senescent cells with age underpins a wide range of pathologies. Senescent …