A new ESI-LC/MS approach for comprehensive metabolic profiling of phytocannabinoids in Cannabis

P Berman, K Futoran, GM Lewitus, D Mukha… - Scientific reports, 2018 - nature.com
Most clinical studies of Cannabis today focus on the contents of two phytocannabinoids:(-)-
Δ9-trans-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), regardless of the fact that …

Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

S Procaccia, GM Lewitus, C Lipson Feder… - Frontiers in …, 2022 - frontiersin.org
Medical Cannabis and its major cannabinoids (−)-trans-Δ9-tetrahydrocannabinol (THC) and
cannabidiol (CBD) are gaining momentum for various medical purposes as their therapeutic …

Chemical profiling of medical cannabis extracts

MM Lewis, Y Yang, E Wasilewski, HA Clarke… - ACS …, 2017 - ACS Publications
Medical cannabis has been legally available for patients in a number of countries. Licensed
producers produce a variety of cannabis strains with different concentrations of …

Cannabinoids from Cannabis sativa L.: A New Tool Based on HPLC–DAD–MS/MS for a Rational Use in Medicinal Chemistry

M Protti, V Brighenti, MR Battaglia… - ACS medicinal …, 2019 - ACS Publications
Cannabis sativa L. represents one of the most widely used source of drugs and drugs of
abuse worldwide. Its biologically active compounds are mainly cannabinoids, including Δ9 …

Methods for quantification of cannabinoids: a narrative review

M Pourseyed Lazarjani, S Torres, T Hooker… - Journal of Cannabis …, 2020 - Springer
Background Around 144 cannabinoids have been identified in cannabis plant, among them
tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most prominent ones. Because …

Analytical techniques for phytocannabinoid profiling of cannabis and cannabis-based products—A comprehensive review

G Stefkov, I Cvetkovikj Karanfilova… - Molecules, 2022 - mdpi.com
Cannabis is gaining increasing attention due to the high pharmacological potential and
updated legislation authorizing multiple uses. The development of time-and cost-efficient …

Non-Cannabinoid Metabolites of Cannabis sativa L. with Therapeutic Potential

H Lowe, B Steele, J Bryant, N Toyang, W Ngwa - Plants, 2021 - mdpi.com
The cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of
different biogenetic classes. In addition to economic value, many of these phytochemicals …

Phytocannabinomics: Untargeted metabolomics as a tool for cannabis chemovar differentiation

A Cerrato, C Citti, G Cannazza, AL Capriotti… - Talanta, 2021 - Elsevier
Cannabis sativa is traditionally classified according to five chemotypes based on the
concentration of the main phytocannabinoids tetrahydrocannabinol (THC), cannabidiol …

Cannabis: from cultivar to chemovar II—a metabolomics approach to Cannabis classification

A Hazekamp, K Tejkalová… - Cannabis and …, 2016 - liebertpub.com
Introduction: There is a large disparity between the “cultural” language used by patients
using cannabis for self-medication and the “chemical” language applied by scientists to get …

Phytocannabinoid Pharmacology: Medicinal Properties of Cannabis sativa Constituents Aside from the “Big Two”

PB Sampson - Journal of Natural Products, 2020 - ACS Publications
Plant-based therapies date back centuries. Cannabis sativa is one such plant that was used
medicinally up until the early part of the 20th century. Although rich in diverse and interesting …