Background: Nowadays, the use of over-the-counter drugs such as acetaminophen (APAP)
may cause severe liver injury, which can occur not only in high doses but also in therapeutic …

Antipyretic acetaminophen (APAP) is a commonly used drug that generally associates with
liver injury.(-)-Epigallocatechin-3-gallate (EGCG), an active polyphenol extracted from green …

Introduction Acetaminophen (APAP) as an analgesic and antipyretic drug can result to liver
damages while using more than 4 g/day. Therefore, APAP toxicity causes the liver to …

Abstract Effect of ethanol extract of the leaves of Acalypha indica (Euphorbiaceae) was
investigated against acetaminophen-induced hepatic damage. Acetaminophen …

Aim: The ability of ethylacetate extract of Persea americana Mill (avocado) seed to
ameliorate the hepatotoxic effect of acetaminophen in rats was assessed. Methodology …

Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving
mild and moderate pain, but at high doses produces hepatic necrosis. Though, Obeticholic …

Introduction: It has been extensively reported that drug-overdose is the leading cause of liver
injury in the world today. Diets rich in natural antioxidants have been observed to offer …

In this study we investigated the hepatoprotective effects and possible mechanism of Acacia
catechu in acetaminophen (APAP) induced hepatotoxicity using female Wistar rat model …

Background: Acetaminophen overdose is a major cause of drug-induced liver failure.
Objective: To investigate the hepatoprotective effects of Extra Virgin Olive Oil (EVOO) and …

Regarding highly prescription of medicines, in recent years, herbal effects on prevention and
treatment of toxicity induced by various drugs have received a great deal of attention. After …